BACKGROUND Myocardial infarction (MI) is a heart condition caused by the suspension of blood circulation in a part of the myocardium. There are different risk factors contributing to a heart attack. Some believe that endorphins and endogenous opioids play an important role in causing MIs. OBJECTIVES This study intended to determine the relationship between opium dependency and mortality rate ...

BACKGROUND Postoperative cognitive dysfunction, especially delirium commonly occurs after cardiac surgery. Clinical evidences suggest an increase in delirium in opium abusers after Coronary Artery Bypass Graft (CABG) surgery. In this study, the prevalence of delirium in addict (opium user) and nonaddict patients after CABG were compared. METHODS In a cross-sectional study after obtaining inst...

background: in patients with hepatitis b and c, environmental factors such as smoking and alcohol can cause liver fibrosis progression. but opium effects on liver fibrosis progression are not clear. this study was designed to assess the relationship of opium user and liver fibrosis progression. methods: in this case-control study, sixty patients in hepatitis b group and sixty patients in hepati...

BACKGROUND Due to this belief that opium may have beneficial effects on diabetes or cardiovascular risk factors, the present study aimed to assess the potential and possible effects of opium consumption on diabetes control and some cardiovascular risk factors in diabetic patients. METHODS This study enrolled 374 diabetic subjects from diabetes care centers in Kerman, Iran, including opium use...

Natural opium is a popular seasonal alternation for substance dependent people. Its processing, way of using, experience and change of habits was the aim of our study carried out via anonymous questionnaire and directed interview. 47 questionnaires were obtained. According to our results natural opium has been abused by people 19-42 years old, more than a half of them were male. Basic drug were...

BACKGROUND Lung cancer is the leading cause of cancer-related death worldwide, and half of all incident lung cancers are believed to occur in the developing countries, including Iran. OBJECTIVE We investigated the association of opium with the risk of lung cancer in a case-control study. METHODS We enrolled 242 cases and 484 matched controls in this study. A questionnaire was developed, con...

Article type: Short communication Objective(s): The aim of this study was to determine the important molecules involved in apoptosis induction by opium in Jurkat cell line. Materials and Methods: Jurkat cells were incubated 48 hrs with 2.86×10-5 g/ml concentration of opium and apoptosis as well as expression levels of related molecules were measured. Results: Our results demonstrated that 50.3±...

Opium consumption is increasing in some eastern societies, where it is grown. We investigated the effect of opium smoking on plasma atherogenic index and incidence of lethal cardiac arrhythmia, i.e. ventricular tachycardia (VT) and ventricular fibrillation (VF) in rabbits. Animals were divided into two-, normo- and hyper-cholesterolemic main groups fed with normal or high cholesterol diet prior...

The importance of opium as a cash crop among the Hmong 1 in north Thailand is widely known and has been studied in detaii.2 The association between the Hmong and Yunnanese "Haw" traders, through whom the Hmong have traditionally marketed opium, is also well known. It is a common misconception, however, that opium plays a central role in Hmong culture. It has, for example, apparently little or n...

BACKGROUND Opium is one of the most common substances used worldwide with variable epidemiologic features in different regions. This study was performed in southern Iran, to find the epidemiology of opium use and its association with different factors and diseases. METHODS This cross-sectional study was performed on baseline data extracted from Pars Cohort Study performed in Valashahr, a rura...