نتایج جستجو برای: tissue plasminogen activator

تعداد نتایج: 954526  

2005
Vladimir Benes Joseph M. Zabramski Alfredo Puca

We conducted a randomized, blinded controlled trial to test the efficacy of fibrinolytic therapy with tissue plasminogen activator and urokinase in the treatment of acute embolic stroke. Embolic stroke was simulated in rabbits by injecting three 0.5x0.5 mm fragments of autologous arterial thrombus harvested from a traumatized auricular artery. Thirty minutes after embolization the rabbits were ...

Journal: :Stroke 2012
Israel Fernández-Cadenas Alberto Del Río-Espínola Dolors Giralt Sophie Domingues-Montanari Adoracion Quiroga Maite Mendióroz Agustin Ruíz Marc Ribó Joaquin Serena Victor Obach Mari Mar Freijo Joan Martí-Fábregas Pilar Delgado Joan Montaner

BACKGROUND AND PURPOSE There is a great interindividual variability among patients with acute ischemic stroke regarding the response to intravenous tissue-type plasminogen activator treatment. The aim of this study was to identify genetic variants associated with recanalization, and thus treatment efficacy, after tissue-type plasminogen activator administration. METHODS A total of 140 single ...

2006
LILIAN TENGBORN

Fibrinolytic components after venous occlusion and concentrations of tissue plasminogen activator inhibitor were studied in 100 consecutive patients with confirmed recurrent deep vein thrombosis or pulmonary embolism. After 20 minutes of venous occlusion the fibrinolytic response was decreased in 33 patients, as measured both amidolytically with S-2251 and on fibrin plates. Two different mechan...

Journal: :Chest 1992
M R Jackson G P Clagett

Abbreviations: ACD 5 absolute claudication distance; CI 5 confidence interval; INR 5 international normalized ratio; LMWH 5 low-molecular-weight heparin; MI 5 myocardial infarction; NASCET 5 North American Symptomatic Carotid Endarterectomy Trial; PGE1 5 prostaglandin E1; PGI2 5 prostaglandin I2; PTFE 5 polytetrafluoroethylene; rtPA 5 recombinant tissue plasminogen activator; tPA 5 tissue plasm...

2016
Maria Khan

Submit Manuscript | http://medcraveonline.com Abbreviations: UAE: United Arab Emirates; NINDS rtPA: Neurological Disorders and Stroke recombinant tissue plasminogen activator; tPA: tissue Plasminogen Activator; CT: Computerized Tomography; mRS: modified Rankin Scale; TOAST: Trial of Org 10172 in Acute Stroke Treatment criteria; NIHSS: National Institute of Health Stroke Scale; SPSS: Statistical...

Journal: :Journal of clinical pathology 1991
S E Heard P Revell L J Holland A D Hurdle G F Savidge

Two important haematological problems were found in an otherwise healthy 78 year old man: chronic myelomonocytic leukaemia; and a complex, acquired, hyperfibrinolytic bleeding disorder characterized by prolonged coagulation times, deficiency of coagulation factors V, X, and XI, anti-thrombin III and proteins C and S, with high concentrations of circulating tissue plasminogen activator, and low ...

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