A numerical algorithm is presented for solving one nonlinear equation in one real variable. Given Fx with brackets A and B, i.e., sign(T^) = -sign^g) * 0, the algorithm finds a zero of F, A < X < B. Alternately, a crossover pair is found, i.e., (X, Y): sign(Fx) = signify) * 0 where there is no floating-point number in the system between X and Y. This feature allows full use of machine precision...

OBJECTIVE The first Phase I study of autologous tolerogenic dendritic cells (Tol-DCs) in Type 1 diabetes (T1D) patients was recently completed. Pancreatic islet transplantation is an effective therapy for T1D, and infusion of Tol-DCs can control diabetes development while promoting graft survival. In this study, we aim to systematically review islet allograft survival following infusion of Tol-...

The recombinant plasmid RP4-TOL was transferred into Caulobacter crescentus at a high frequency, and the plasmid was maintained for at least 50 generations. C. crescentus cells which contained RP4-TOL grew on all the aromatic compounds that the plasmid normally allowed Pseudomonas putida to grow on. Reciprocal transfers from C. crescentus donor to P. putida or Escherichia coli recipients were l...

We present an adaptive multilevel Monte Carlo (MLMC) method for weak approximations of solutions to Itô stochastic differential equations (SDE). The work [Oper. Res. 56 (2008), 607–617] proposed and analyzed an MLMC method based on a hierarchy of uniform time discretizations and control variates to reduce the computational effort required by a single level Euler–Maruyama Monte Carlo method from...

BACKGROUND Offering a trial of labor (ToL) after previous caesarean section (CS) is an important strategy to reduce short- and long-term morbidity associated with repeated CS. We compared maternal and perinatal outcomes between ToL and elective repeat caesarean section (ERCS) at a district hospital in rural Rwanda. METHODS Audit of women's records with one prior CS who delivered at Ruhengeri ...

Background Pomegranate can inhibit cytochrome P450 (CYP) 2C9 activity, which is largely responsible for the metabolism of sulfonylureas. The present study was undertaken to evaluate the pharmacokinetic and pharmacodynamic interaction of pomegranate and tolbutamide (TOL) against diabetic-induced complications. Methods Diabetes was induced via administration of alloxan (150 mg/kg, intraperitone...

Two hundred twenty women with prior cesarean section were delivered at our institution between January 1987 and February 1990. Vaginal delivery was achieved in 111 (66%) of 169 patients given a trial of labor (TOL). Success of TOL correlated positively with the number of prior vaginal deliveries (P less than 0.05) and inversely with the number of prior cesarean sections (P less than 0.005). Mat...

Reduction of [U(Ts(Tol))(Cl)(μ-Cl)U(Ts(Tol))(THF)2] [2, Ts(Tol) = HC(SiMe2NAr')3; Ar' = 4-MeC6H4)] with KC8 in toluene afforded the new arene-bridged diuranium complex [{U(Ts(Tol))}2(μ-η(6):η(6)-C6H5Me)] (3); combined structural, spectroscopic, magnetic, and computational analyses unambiguously confirm that the uranium centres in 3 are in the +5 oxidation state and the toluene is a 10π-tetraanion.

An increased awareness of environmental protection and sustainable production raise the necessity incorporating selection low nitrogen-tolerant winter wheat cultivars for high yield quality in breeding process. This can be assisted by using stress screening indices. Our study aimed to evaluate compare a number indices determine select most nitrogen deficiency-tolerant further breeding. The expe...