bioassays were conducted to assess the contact toxicity of two plant essential oils against adults of sitophilus granarius (l.) and tribolium confusum jacquelin du val. essential oils were extracted from seeds of carum copticum l. and cuminum cyminum l. contact toxicity was assessed by topical application and adult mortality was counted 1, 2, 6 and 24 h after exposure. bioassays were carried ou...

the topical delivery of non-steroidal anti-inflammatory drugs (nsaids) such as ibuprofen has been explored as a potential method of avoiding the first pass effects and the gastric irritation, which may occur when used orally. ibuprofen is formulated into many topical preparations to reduce the adverse effects and simultaneously avoid the hepatic first-pass metabolism as well. however, it is dif...

PubChem's BioAssay database (https://pubchem.ncbi.nlm.nih.gov) has served as a public repository for small-molecule and RNAi screening data since 2004 providing open access of its data content to the community. PubChem accepts data submission from worldwide researchers at academia, industry and government agencies. PubChem also collaborates with other chemical biology database stakeholders with...

A laboratory bioassay was developed for testing tarnished plant bug populations for resistance development to the neonicotinoid insecticides imidacloprid and thiamethoxam. The bioassay allows for the determination of LC50 values by feeding known doses of the insecticides to adult tarnished plant bugs in a honey-water solution. Field populations of plant bugs from several locations in the mid-So...

-Peripheral-blood basophils were counted, in thick smears, in samples from patients with primary bronchial carcinoma, from patients in the same wards and from normal individuals. The median counts for patients with other chest conditions (15-5/4d) and bronchial-carcinoma patients free of tumour months to years after resection (16/1l) did not differ from those for normal individuals (19/1,u), bu...

BACKGROUND Experimental investigation of stroke, in particular the evaluation of therapeutic maneuvers, is difficult because even well-controlled experiments show considerable variability. Optimal use of resources requires efficient statistical analysis. SUMMARY OF REVIEW A body of experience in pharmacology that is directly applicable to stroke studies is reviewed. The general approach, thou...

the objective of this study was to determine the effectiveness of topical administration of honey in prevention of or reduction in post-surgical peritoneal adhesions in dog. the study was conducted on 18 adultfemale mixed-breed dogs with a mean ± sd weight of 20 ± 4.25 kg. a standardized surgical trauma (serosaltrauma model) was made in the dogs’ descending colon to induce adhesion formation. t...

purpose: to present two patients with acute corneal hydrops, superimposed with infectious keratitis using topical steroids. patients and findings: the first case was a 44-year-old man with acute corneal hydrops in his left eye which was on topical steroids for one week. visual acuity was hand motion at presentation and there was a large epithelial defect with stromal infiltration and corneal ed...

an agar well diffusion bioassay method for determination of clarithromycin in human plasma, using micrococcus luteus atcc 9341 as the assay organism, was compared with a selective high-performance liquid chromatographic (hplc) method with uv detection. spiked plasma was used to prepare standard and control samples for both methods. the results of the bioassay analyses with spiked plasma samples...