In this work, we present a fully automated lung CT cancer diagnosis system, DeepLung. DeepLung contains two parts, nodule detection and classification. Considering the 3D nature of lung CT data, two 3D networks are designed for the nodule detection and classification respectively. Specifically, a 3D Faster R-CNN is designed for nodule detection with a U-net-like encoder-decoder structure to eff...

Background: Serum lactate dehydrogenase (LDH) concentration is an indicator for tissue injury. It may be secreted locally in many conditions. For the first time, this study was performed to investigate the value of LDH level in bronchoalveolar lavage fluid (BALF) in differentiation of benign from malignant single pulmonary nodules (SPNs) and to assess its relationship with serum LDH levels. Met...

Lugol’s solution, named after the French Physician JGA Lugol (1786–1851), has a high affinity for glycogen in non-keratinised squamous epithelium. Since the 1960s when Lugol’s iodine was first used to investigate oesophageal diseases, advances in the field of diagnostic endoscopy have resulted in its increasing use to detect early mucosal abnormalities and to target biopsies from unstained area...

Refer to the literature of lung nodule classification, many studies adopt Convolutional Neural Networks (CNN) to directly predict the malignancy of lung nodules with original thoracic Computed Tomography (CT) and nodule location. However, these studies cannot tell how the CNN works in terms of predicting the malignancy of the given nodule, e.g., it’s hard to conclude that whether the region wit...

computer aided pulmonary nodule detection has been among major research topics lately to help for early treatment of lung cancer which is the most lethal kind of cancer worldwide.some evidence suggests that periodic screening tests with the ct of patients will help in reducing the mortality rate caused by the lung cancer. acomplete and accurate computer aided diagnosis (cad) system for detectio...

Lugol’s solution, named after the French Physician JGA Lugol (1786–1851), has a high affinity for glycogen in non-keratinised squamous epithelium. Since the 1960s when Lugol’s iodine was first used to investigate oesophageal diseases, advances in the field of diagnostic endoscopy have resulted in its increasing use to detect early mucosal abnormalities and to target biopsies from unstained area...

Introduction solitary thyroid nodule is defined as a single discrete mass of abnormal tissue in an otherwise normal thyroid gland. In different studies, thyroid nodules were found in 4-7 percent of American adults. Thyroid nodule is probably one of the commonest endocrine problems in the wold. In a report from the thyroid clinic, IPGMR, Dhaka, 32.67 percent of all thyroid patients had solitary ...

OBJECTIVE The relative expression of the apoptotic protein Fas and the anti-apoptotic protein Bcl-2 were investigated in thyrocytes from patients with non-toxic nodular goiter (NTG, n=20) and Hashimoto's thyroiditis (HT, n=5), who underwent fine-needle aspiration biopsy for diagnostic reasons. On the basis of the clinical and cytological findings, the patients with NTG were sub-classified into ...