Safranal, the main component of Crocus sativus essential oil, is thought to be the main cause of saffron unique odor. It is now about eighty years that this compound has been discovered and since then different scientific experiments have been done investigating its biological-pharmacological activities. Safranal effects in CNS have been more attractive to scientists and an escalating number of...

safranal, the main component of crocus sativus essential oil, is thought to be the main cause of saffron unique odor. it is now about eighty years that this compound has been discovered and since then different scientific experiments have been done investigating its biological-pharmacological activities. safranal effects in cns have been more attractive to scientists and an escalating number of...

background and objectives: the plants belonging to the genus heliotropium l. (boraginaceae) are the main sources of toxic pyrrolizidine alkaloids (pas). in the present study, we have investigated the pas of the aerial parts of heliotropium transoxanum bunge, a perennial species native to iran. methods: silica gel column chromatography and silica gel ptlc were applied for the isolation of pas pr...

The influence of oligosaccharides (α-cyclodextrin, β-cyclodextrin and γ-cyclodextrin), a polysaccharide, sodium hyaluronate (NaHy), on the diffusion aqueous solutions cobalt chromium chlorides has been investigated. Cobalt are constituents metal alloys for biomedical use, including dental prostheses. Thus, release these ions in human body can lead to harmful biological effects. interaction with...

Background: Acute poisonings are common presentations to emergency departments (EDs) worldwide and require rapid assessment. Consultant emergency physicians (EPs) faced with various toxicological presentations must initiate rapid investigations and empirical management. This study aimed to determine emergency department doctors’ level of knowledge and confidence in toxicological presentations, ...

Toxicological data or PBPK models were not available for any of the threeor four-component submixtures. Toxicological data were available only for the binary mixture of carbon monoxide and methylene chloride; toxicological data on the other binary submixtures were not located. PBPK models for methylene chloride generally contain components describing the metabolism of methylene chloride to form...