Activity of secreted alkaline phosphatase (SEAP) produced by transfected cells is rapidly down-regulated by endoplasmic reticulum (ER) stress independent of transcriptional regulation. This phenomenon was observed in a wide range of cell types triggered by various ER stress inducers. The magnitude of the decrease in SEAP was proportional to the extent of ER stress and inversely correlated with ...

Synopsis The stress vs strain curves in dense colloidal dispersions under start up shear flow are investigated combining experiments on model core shell microgels, computer simulations of hard disk mixtures, and mode coupling theory. In dense fluid and glassy states, the transient stresses exhibit first a linear increase with the accumulated strain, then a maximum (stress overshoot) for strain ...

We investigate stresses and particle motion during the start-up of flow in a colloidal dispersion close to arrest into a glassy state. A combination of molecular dynamics simulation, mode-coupling theory and confocal microscopy experiments is used to investigate the origins of the widely observed stress overshoot and (previously not reported) super-diffusive motion in the transient dynamics. A ...

BACKGROUND Exercise gated single-photon emission computed tomography (SPECT) using technetium-99m (99mTc)-sestamibi evaluates both myocardial perfusion during stress and wall motion >30 min after the stress, which has the potential to assess not only exercise-induced myocardial ischemia but also the development of myocardial stunning. METHODS AND RESULTS To evaluate the incidence of post-stre...

Adenosine is a short-acting coronary vasodilator, and it is widely used during pharmacological stress myocardial perfusion imaging. It has a well-established safety profile, and most of its side effects are known to be mild and transient. Until now, coronary vasospasm has been rarely reported as a side effect of adenosine during or after adenosine stress test. This study reports a case of coron...

our aim was to report techniques and our experience in one-stage angioplasty and stenting of ostium of left common carotid and left internal carotid arteries in an octogenarian man with transient ischemic attack, who was completely recovered from neurologic insults short time after the procedure. an 81-year-old man presented with a transient ischemic attack. neurologic examination showed left s...

background primary congenital hypothyroidism (ch) is the most common treatable cause of mental retardation and can be classified into permanent and transient types. the purpose of this study was to determine the prevalence of permanent and transient congenital hypothyroidism (ch) in hamadan, west province of iran. methods the study population included all cases with primary congenital hypothyro...

background: transient and stable transformation of host plants are the common techniques to produce transgenic plants. however, the main drawback of stable transformation is the fact that it takes quite a long time to produce a transgenic line. while, transient gene expression is a quick method to produce recombinant proteins in plants.  objective: the main goal of the present study was to eval...

cerebrovascular attack (cva) and transient ischemic attack (tia) are major causes of emergency department visits around the globe. a significant number of these patients may experience repeat attacks if left untreated. several risk stratifying scoring systems have been developed in recent years to point out the high risk patients. abcd 2 is based on age, blood pressure, clinical status, diabete...

one of the most preventable causes of mental and growth retardation is congenital hypothyroidism (ch). this study tries to investigate growth and mental outcome of patients with ch. since november 2006 and november 2007 in guilan province, north of iran, all neonates who were diagnosed with ch, evaluated for etiology of ch by laboratory follow up, thyroid sonography or scan. growth and developm...