Neuromyelitis optica (also known as Devic's disease or Devic's syndrome) is an uncommon disorder in pediatric age group, and is characterized by acute or subacute optic neuritis and transverse myelitis. Here we report an 11- year- old female child with relapsing Neuromyelitis optica (NMO) confirmed by positive NMO- IgG antibody and had clinical recovery with high dose methyl prednisolone t...

Various clinical types of central nerve infection caused by herpes simplex virus (HSV) have been identified, and the clinical features of not only encephalitis and meningitis, but also Mollaret meningitis and Elsberg syndrome, have been clarified (Tyler, 2004; Eberhardt et al., 2004). Myelitis is rare, and it has been mostly reported as ascending myelitis, necrotizing myelitis or myeloradiculit...

Myelopathy manifested clinically as acute longitudinal or transverse myelitis constitutes one of the most severe and rare neuropsychiatric manifestations of systemic lupus erythematosus (SLE) (1-3% of patients). Myelitis has been observed less commonly in other connective tissue diseases, mostly in antiphospholipid syndrome, and rarely in Sjögren's syndrome, Behçet's disease and mixed connectiv...

Myelin-Oligodendrocyte Glycoprotein (MOG) is an adhesive molecule responsible for myelin sheath structural integrity and maintenance. Patients with spectrum of inflammatory demyelinating disease particularly in central nervous system are reported to have antibodies against this protein. Diseases such as multiple sclerosis, clinically isolated syndrome, neuro-myelitis optica (NMO) spectrum disor...

Myelitis is a rare complication of Schistosoma mansoni, and is characterized by a dramatic involvement of the lower part of the spinal cord [1 , 2]. Early antischistosomal therapy is able to improve markedly clinical signs [3, 4J. Myelography and CT (3, 5-1 OJ are normal in most cases of Schistosoma mansoni transverse myelitis (2, 1 OJ . As far as we know, no MR studies have been reported. We p...

OBJECTIVE To determine the presenting features and etiological classification of acute transverse myelitis (ATM) at Aga Khan University Hospital, a tertiary care hospital in Pakistan. METHODS Twenty consecutive patients of ATM (1996-2003) fulfilling a preset criterion were analyzed for demographic features, clinical presentation, laboratory investigations and neuro-imaging. RESULTS Half of ...