Although rare, the morbidity and mortality from brain tumors are significant. Chemotherapy has made only a small impact on these tumors. The human T98G glioblastoma multiforme cell line was used as a brain tumor model. The protein kinase Cbeta inhibitor 317615 x 2HCl was not highly cytotoxic toward T98G cells in culture and was additive in cytotoxicity with carmustine (BCNU). When nude mice bea...

Treatment must be initiated promptly in any patient newly diagnosed with tuberculosis. The choice for initial treatment is a regimen ideally proven in a clinical trial to have high efficacy in preventing treatment failure and relapse. Over time, the choice of this initial regimen has changed with ever increasingly efficacious and effective drug combinations. The regimen is only changed when the...

Treatment of latent tuberculosis infection (LTBI) is essential for eradicating tuberculosis (TB). Moreover, the patient adherence is crucial in determining the effectiveness of TB control. Isoniazid given by DOTS daily for 9 months (9H) is the standard treatment for LTBI in Taiwan. However, the completion rate is low due to the long treatment period and its side effects. The combined regimen us...

conclusions ap did not prevent utis and resulted in more resistant organisms requiring iv antibiotics. discontinuing ap allowed the return of susceptibility to oral antimicrobials and significantly improved gfr in those children who had previously been on ap. adherence to a catheterization regimen with prompt treatment of symptomatic uti conserved renal function and prevented selection of resis...

Leprosy will continue to be a public health problem for several decades. The World Health Organization (WHO) recommends that, for treatment purposes, leprosy cases be classified as either paucibacillary or multibacillary (MB). A uniform leprosy treatment regimen would simplify treatment and halve the treatment duration for MB patients. The clinical trial for uniform multidrug therapy (U-MDT) fo...

We report treatment results obtained with a modified Stanford V regimen in 32 patients with advanced Hodgkin's lymphoma (stage II bulky disease, III, IV). Treatment results were not superior to those achieved with conventional treatment (ABVD) in terms of complete remission and survival rates (progression-free survival and overall survival at 3 years: 66% and 91%, respectively).

An irrigation experiment was conducted with three cultivars (Hass, Ettinger and Fuerte) in the avocado plantation of the Akko Experiment Station, Israel, during 1974-80 to determine the effect of irrigation regimen in spring and autumn on tree growth and productivity. Two treatments (wet and dry) were tested in the spring and in the autumn. In spring the trees receiving the wet treatment were i...