This study was conducted to evaluate changes in the composition of a poly-L-lactic D-lactic acid and trimethylene carbonate (PLDLA-TMC) sheet after insertion into the human body. A 35-year-old woman had an orbital fracture that was reconstructed using a PLDLA-TMC sheet. During iliac bone grafting for enophthalmos 190 days after the insertion, the sheet was removed and analyzed using gel permeat...

Objetivo: Avaliar a prevalência de transtorno mental comum entre estudantes medicina da UnC - Mafra/SC e estimar possíveis correlações TMC fatores associados. Método: Foi realizado um estudo transversal, abrangendo 238 medicina. O questionário utilizado foi autoaplicável anônimo. Foram coletados dados socioeconômicos, informações sobre o curso/processo ensino-aprendizagem aspectos psicossociais...

Self-assembling polymeric surfactant, mmePEG(750)P(CL-co-TMC) [monomethylether poly(ethylene glycol)(750)-poly(caprolactone-co-trimethylene carbonate)], increases drug solubility and crosses an enterocyte monolayer both in vitro and in vivo. The aims of the present work were to investigate whether mmePEG(750)P(CL-co-TMC) polymers can diffuse passively through lipid bilayer using parallel artifi...

Transition metal carbides (TMCs) and transition metal nitrides (TMNs) have attracted attention as promising electrocatalysts that could replace noble metals of high price and limited supply. Relative to parent metals, TMC and TMN behave like noble metals for electrochemical reactions such as oxidation of hydrogen, CO and alcohols, and reduction of oxygen. When TMC and TMN are combined with othe...

Sensory transduction in auditory and vestibular hair cells requires expression of transmembrane channel-like (Tmc) 1 and 2 genes, but the function of these genes is unknown. To investigate the hypothesis that TMC1 and TMC2 proteins are components of the mechanosensitive ion channels that convert mechanical information into electrical signals, we recorded whole-cell and single-channel currents f...

We present P(TMC-co-DLLA) copolymer with the molar ratio of TMC: DLLA = 15: 85 was used to systematic study of in vivo and in vitro degradation behaviors. Dense homogeneous copolymer specimens were prepared by compression molding method. The in vitro and in vivo degradation were, respectively, performed at simulative body condition and implanted into rat's subcutaneous condition. Investigations...

ubiquitin, and then degraded by a proteasome in an ATP dependent manner1^ The catalytic core of the proteasome is the 20S proteasome. New20S proteasome inhibitors would contribute to further understanding of the system2~4\ In the course of our screening program, wehave isolated several classes of 20S proteasome inhibitors including (i) the novel cyclic peptides, TMC-95s, and (ii) the new member...

background: enterohemorrhagic escherichia coli (ehec) o157:h7 is an infectious zoonotic pathogen causing human infections. these infections, in some cases, can lead to hemolytic uremic syndrome and its life-threatening complications and even death worldwide. the first intimate bacterial adhesion, intimin (i), with its own receptor translocated intimin receptor (tir) and e. coli secreted protein...

The consolidation of fiber-reinforced titanium matrix composite (TMC) monotapes produced by spray deposition is an important step in the manufacture of TMC components. The performance of this class of composites is controlled by fiber-matrix properties and by the composite’s relative density, fiber microbending stress/fracture and by the interfacial reaction layer thickness at the fiber-matrix ...

There is evidence of angiogenesis being induced after transmyocardial laser revascularization (TMLR), although the precise mechanism has not been fully elucidated. This study was designed to examine whether or not blood flow from the left ventricle through the channels is essential for angiogenesis following TMLR. Ten dogs underwent the creation of two types of laser channels in the left ventri...