UNLABELLED Colloidal particle size is an important characteristic to consider when choosing a radiopharmaceutical for mapping sentinel nodes in lymphoscintigraphy. METHODS Photon correlation spectroscopy (PCS) and transmission electron microscopy (TEM) were used to determine the particle size of antimony trisulfide and rhenium sulfide colloids, and membrane filtration (MF) was used to determi...

Within an extensive systematic analysis of trauma associated fatalities in the German capital city Berlin as well multiple trauma as the isolated traumatic brain injury were figured out as leading cause of death. Moreover the authors were able to identify two hotspots of trauma managementpreclinical care and ICU. Thus they suggest a certain shift of the former asserted „trimodal“ contribution o...

Paraoxonase 1 (PON1) is a member of a tandem 3-gene family localized on human chromosome 7q21-22.1 High-density lipoprotein-associated PON12,3 and PON34,5 are synthesized primarily in the liver, whereas PON2 is ubiquitously expressed.1 PON1 was initially characterized and named for its ability to hydrolyze paraoxon, the toxic oxon metabolite of parathion.6 Although Aldridge6 proposed in 1953 th...

Interindividual variability in polymorphic uridine diphosphate-glucuronosyltransferase 1A1 (UGT1A1) ascribed to genetic diversity is associated with relative glucuronidation level among individuals. The present research was aimed to study the effect of 2 important single nucleotide polymorphisms (SNPs; rs8330 and rs10929303) of UGT1A1 gene on glucuronidation status of acetaminophen in healthy v...

A trimodal locomotor activity pattern has been observed in LEW/Ztm rats. Complete and partial lesions of the suprachiasmatic nucleus (SCN) were used to determine whether the same neural substrate may underlie the circadian rhythms and the ultradian modulation of wheel-running activity in these rats. Whereas sham lesions had little or no effect on the wheel-running activity pattern, complete SCN...

Four alpha genes exist on chromosome 16, but one or more of these genes can be deleted in association with Hemoglobin (Hb)G-Philadelphia in cis to alpha-thalassemia-2 in African-Americans. Therefore, the proportion of HbG-Philadelphia in HbG heterozygotes is trimodal at about 25% for alphaGalpha/alpha alpha, 33% for alphaG-/alpha alpha, and 50% for alphaG-/alpha alpha in patients with HbA. Thos...

In Iran, there are no studies addressing trauma death timing and factors affecting time of death after injuries. This study aimed to examine time distribution of trauma deaths in an urban major trauma referral center with respect to victims' injury characteristics during 2010 to 2015.This was a cross-sectional study of adult trauma-related in-hospital deaths resulting from traffic-related accid...