نتایج جستجو برای: tropane alkaloid
تعداد نتایج: 7458 فیلتر نتایج به سال:
Calystegines are hydroxylated nortropane alkaloids derived from the tropane alkaloid biosynthetic pathway. They are strong glycosidase inhibitors and occur in vegetables such as potatoes, tomatoes, and cabbage. Calystegine accumulation in root cultures was described to increase with carbohydrate availability. Whether this is indicative for the in planta situation is as yet unknown. Potatoes are...
Nicotine, the signature alkaloid of Nicotiana species responsible for the addictive properties of human tobacco smoking, functions as a defensive neurotoxin against attacking herbivores. However, the evolution of the genetic features that contributed to the assembly of the nicotine biosynthetic pathway remains unknown. We sequenced and assembled genomes of two wild tobaccos, Nicotiana attenuata...
A strain of Rhodococcus designated MB1, which was capable of utilizing cocaine as a sole source of carbon and nitrogen for growth, was isolated from rhizosphere soil of the tropane alkaloid-producing plant Erythroxylum coca. A cocaine esterase was found to initiate degradation of cocaine, which was hydrolyzed to ecgonine methyl ester and benzoate; both of these esterolytic products were further...
Plants remain a major source of new drugs, leads and fine chemicals. Cell cultures deriving from plants offer a fascinating tool to study plant metabolic pathways and offer large scale production systems for valuable compounds - commercial examples include compounds such as paclitaxel. The major constraint with undifferentiated cell cultures is that they are generally considered to be genetical...
Article history: Received on: 05/11/2012 Revised on: 29/11/2012 Accepted on: 18/12/2012 Available online: 28/02/2013 Anisodus acutangulus hairy roots were grown in N6 medium which was optimal for growth and alkaloid production. The cell biomass and alkaloid yield reached 2.7 g l and 3.9 mg l (dry weight) respectively in sucrose medium, higher than those obtained in other carbon source media. 90...
plants are the important sources of drugs. secondary metabolites are responsible for therapeutic propertiesin plants. three compounds including (-)-hyoscyamine, its racemate atropine, and scopolamine (hyoscine) are the most famous tropane alkaloids in the solanaceae familly. nowadays, attempts to developthese alkaloids in biotechnological procedures which are principally based on the hairy root...
The structure of a salt of diprotonated endo-3-amino-tropane crystallized with a copper(II) anionic cluster is reported, viz. (C8H18N2)[CuCl3(NO3)(H2O)]. Neither ion in the salt has been structurally characterized previously. In the crystal, the ions pack together to form a three-dimensional structure held together by a network of inter-molecular N-H⋯O, O-H⋯Cl and N-H⋯Cl hydrogen-bonding inter-...
Background: The use of the desirability function approach combined with the response surface methodology (RSM), also called Desirability Optimization Methodology (DOM), has been successfully applied to solve medical, chemical, and technological questions. It is particularly effi cient for the determination of the optimal conditions in natural or industrial processes involving d...
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