نتایج جستجو برای: tumor growth factor

تعداد نتایج: 1743425  

Journal: :Clinical cancer research : an official journal of the American Association for Cancer Research 2000
A Eggert N Ikegaki J Kwiatkowski H Zhao G M Brodeur B P Himelstein

Angiogenesis is essential for tumor growth and metastasis and depends on the production of angiogenic factors by tumor cells. Neuroblastoma (NB) is a common pediatric tumor of neural crest origin, which is biologically and clinically heterogeneous. Increased tumor vascular index correlates with poor outcome of NB. To determine which angiogenic factors contribute to NB angiogenesis and thereby s...

2014
Sung Hoon Choi Ae Ri Chung Wonseok Kang Jun Yong Park Mi Sol Lee Shin Won Hwang Do Young Kim Seung Up Kim Sang Hoon Ahn Seungtaek Kim Kwang-Hyub Han

Dimerization of hypoxia-inducible factor-1 beta (HIF-1β) [aryl hydrocarbon receptor nuclear translocator (ARNT)] with HIF-1α is involved in various aspects of cancer biology, including proliferation and survival under hypoxic conditions. We investigated the in vitro mechanism by which silencing of HIF-1β leads to the suppression of tumor cell growth and cellular functions. Various hepatocellula...

Journal: :Annals of surgery 2007
Kenneth Meredith Dieter Haemmerich Chen Qi David Mahvi

OBJECTIVE The purpose of this study was to examine the effects of radiofrequency ablation (RFA) on tumor growth and growth factor expression in a murine model. BACKGROUND Surgical excision remains the only potentially curative therapy for hepatic malignancies. Tumor growth in the remaining liver may be accelerated after resection. The mechanism of this enhanced tumor growth remains unexplaine...

Journal: :The Journal of biological chemistry 2008
Akio Soeda Akihito Inagaki Naoki Oka Yuka Ikegame Hitomi Aoki Shin-Ichi Yoshimura Shigeru Nakashima Takahiro Kunisada Toru Iwama

A cancer stem cell population in malignant brain tumors takes an essential part in brain tumor initiation, growth, and recurrence. Growth factors, such as epidermal growth factor, fibroblast growth factor-2, vascular endothelial growth factor, platelet-derived growth factor, and hepatocyte growth factor, are shown to support the proliferation of neural stem cells and also may play key roles in ...

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