Fetal lung maturity assessment in twin pregnancy has been discussed, but is still controversial. The purpose of this study is to predict the occurrence of respiratory distress syndrome (RDS) using lamellar body count (LBC) and analyze the validity of LBC for fetal lung maturity assessment in twin pregnancy. Three-hundred two amniotic fluid samples were obtained at cesarean section from 29 to 38...

INTRODUCTION Spontaneous rupture of utero-ovarian vessels is a rare cause of haemoperitoneum in pregnancy, leading to significant maternal and foetal morbidity and mortality. Aetiopathogenesis of this condition is still unclear. Establishing clinical diagnosis of this condition is difficult, but very important. Clinical symptoms are nonspecific, and the diagnosis is usually made at laparotomy. ...

BACKGROUND Women with twin pregnancy are at high risk for spontaneous preterm delivery. Progesterone seems to be effective in reducing preterm birth in selected high-risk singleton pregnancies, albeit with no significant reduction in perinatal mortality and little evidence of neonatal benefit. We investigated the use of progesterone for prevention of preterm birth in twin pregnancy. METHODS I...

Lamotrigine is frequently used to manage epilepsy during pregnancy. However, some major and minor birth defects are reported with lamotrigine monotherapy. This study is a case series report on 20 epileptic women who were receiving lamotrigine in their pregnancy. Apart from the normal pregnancies and births, in our study three patients gave birth to healthy twins, two vanished twin syndromes occ...

P A twin pregnancy with a complete hydatidiform mole with a coexistent foetus (CHMF) is a rare condition that typically results in poor pregnancy outcomes. For patients with refractory vaginal bleeding, termination of pregnancy is more appropriate. However, unified methods for termination remain to be explored. In the present study, we reviewed the termination measures in four cases of twin pre...

Objective: To provide a Canadian consensus document with recommendations on prenatal screening for and diagnosis of fetal aneuploidy (e .g ., Down syndrome and trisomy 18) in twin pregnancies . Options: The process of prenatal screening and diagnosis in twin pregnancies is complex . This document reviews the options available to pregnant women and the challenges specific to screening and diagno...

BACKGROUND Despite twinning being common in Africa, few prospective twin studies have been conducted. We studied twinning rate, perinatal mortality and the clinical characteristics of newborn twins in urban Guinea-Bissau. METHODS The study was conducted at the Bandim Health Project (BHP), a health and demographic surveillance site in Bissau, the capital of Guinea-Bissau. The cohort included a...

Risk of birth defects in multiple pregnancies Frequency of monozygotic twins remains constant, while dizygotic twins become more frequent as maternal age increases. In these cases the risk that at least one fetus is aneuploid will be twice the maternal age risk for a singleton while the probability of both fetuses being involved is minimal. Dizygotic twins have a six fold increased risk that on...

The aim of the article is to present actual knowledge concerning twin pregnancy. After the physiological changes observed during such pregnancy, main complications such as intrauterine growth restriction (IUGR), prematurity, premature rupture of membranes (PROM) and hypertension are discussed. The paper ends with discussion about the possible routes of delivery in twin pregnancy.

The aim of this study is to describe the perinatal outcomes twin pregnancies complicated with previable PPROM (PV-PPROM) and expectant management. Retrospective review including women pregnancy before 24+0 weeks ongoing pregnancy, between 2015-2022, in our center. Exclusion criteria were: intrauterine fetal demise (IUFD) one fetus diagnosis, clinical chorioamnionitis at presentation, monoamniot...