BACKGROUND The relevance of B-cell dysfunction for progression to AIDS among human immunodeficiency virus (HIV)-infected individuals has not been clearly defined. We evaluated the association between circulating κ and λ free light chains (FLCs), which are markers of B-cell dysfunction, and risk of developing an AIDS-defining opportunistic infection in HIV-infected men. METHODS The study inclu...

The industrial applications of fuzzy logic controllers (FLC) for complex, nonlinear, time varying processes with time delay mark a considerable progress. It is inspired by the recent theoretical achievements in the FLC’s design and tuning related to system stability and robustness. The design and the FLC simplicity are of crucial importance. There exists an easy design and tuning procedure for ...

Artificial heart pump (AHP) is employed to replace the native damaged and perform its functions. Bearingless brushless DC (BBLDC) motors are used for implementation of AHP. BBLDC motor a highly nonlinear model with uncertainties mathematical hard be found accurately. In this paper, simulated. Proportional plus integral (PI) controller proposed control rotor suspension current. Furthermore, type...

Vernalization, the acceleration of flowering by the prolonged cold of winter, ensures that plants flower in favorable spring conditions. During vernalization in Arabidopsis, cold temperatures repress FLOWERING LOCUS C (FLC) expression in a mechanism involving VERNALIZATION INSENSITIVE 3 (VIN3), and this repression is epigenetically maintained by a Polycomb-like chromatin regulation involving VE...

OBJECTIVE Immunoglobulin free light chain (FLC) abnormalities are common in patients with monoclonal gammopathies and the kidneys are the most affected organs. Immunoassays that provide quantitative measurement of FLC in serum indicate monoclonal FLC production based on the presence of an abnormal FLC kappa:lambda (κ:λ) ratio. The aim of this study was to assess the utility of serum FLC measure...

This paper addresses the problem of trajectory tracking control in an autonomous, wheeled, mobile robot of unicycle type using Fuzzy Logic. The Fuzzy Logic Control (FLC) is based on a backstepping approach to ensure asymptotic stabilization of the robot’s position and orientation around the desired trajectory, taking into account the kinematics and dynamics of the vehicle. We use the Mamdani in...

During the life cycle of a plant, one of the major biological processes is the transition from the vegetative to the reproductive stage. In Arabidopsis, flowering time is precisely controlled by extensive environmental and internal cues. Gibberellins (GAs) promote flowering, while abscisic acid (ABA) is considered as a flowering suppressor. However, the detailed mechanism through which ABA inhi...

This paper presents the detailed account on the control design for input tracking of a buck converter driven dc motor. Proportional-Integral (PI), Proportional-Integral-type Fuzzy Logic controller (PI-type FLC) and Linear Quadratic Regulator (LQR) are the techniques proposed in this investigation to control the speed of a dc motor. The dynamic system composed from buck-converter/dc motor is con...

Multiple Myeloma is a plasma cell cancer that produces excess Free Light Chains (FLC). Patients with this condition are treated with dialysis and chemotherapy. A previous compartmental model developed by Evans et al. [2006] described the removal of FLC through a hemodialysis membrane. In this model all rate constants were considered linear and the production of FLC a constant input function. It...

A 1.8-million-member D-octapeptide combinatorial library was constructed in which each member comprised a diversity-containing N-terminal pentapeptide and a C-terminal amidated triarginine motif. The C-terminal motif concentrated the library members at the fungal cell surface. A primary screen for inhibitors of Saccharomyces cerevisiae and Candida albicans growth, together with an in vitro seco...