The majority of foot ulcers appear to result from minor trauma in the presence of sensory neuropathy. This best describes the critical triad most commonly seen in patients with diabetic foot ulcers: peripheral sensory neuropathy, deformity, and trauma. All three of these risk factors are present in 65% of diabetic foot ulcers. Calluses, edema, and peripheral vascular disease have also been iden...

ABSTRACT Introduction: Formation of gastric ulcer is a multifactorial process so that vascular changes, mucous secretion, gastric acid and gastrointestinal tract mucous biochemistry are involved in gastric ulcers. Despite therapeutic properties, ibuprofen as a non-steroidal anti-inflammatory drug (NSAID) can cause mucosal lesions in the stomach. In this study, the effect of Matri...

Background Hospitalization causes many pressure ulcers and has important implications for the patient and the economy. Regional hospital Horsens is one of 5 hospitals in Denmark participating in ‘The Danish Safer Hospital Programme’ where one aim is to reduce and prevent pressure ulcers. The target for the hospital is to reduce pressure ulcers to less than 5% and the aim is to, asses the risk o...

Of 212 patients with duodenal ulcer treated with four weeks of one gram daily cimetidine, 25 had ulcers which underwent no reduction in size despite treatment. The effects of tripotassium dicitrato bismuthate (TDB) tablet four times a day or cimetidine 1.6 g daily on the healing of these cimetidine resistant ulcers were compared in a randomised crossover trial. Ten of 12 patients on tripotassiu...

Pressure ulcers can lead to pain, disfigurement, and slow recovery from comorbid conditions. They interfere with activities of daily living, predispose to osteomyelitis and septicemia (1), and are strongly associated with longer hospital stays and mortality. Frailty and chronic illness, both common among older adults, predispose to pressure ulcers (1–3). The prevalence of pressure ulcers is 10%...

Corneal ulcers are probably the most common problem of the canine eye seen in general veterinary practice. Most of these ulcers result from a variety of traumatic and irritating conditions and usually respond well to medical therapy alone, provided they are not too deep. However, indolent ulcers are different: they are chronic superficial ulcers that result from a structural defect of the corne...

Helicobacter pylori is an important risk factor for peptic ulcers. If infection withH pylori is cured, ulcers associated with H pylori do not recur. An H pylori “test and treat” strategy for patients with peptic ulcers having long term antisecretory treatment has been suggested, in the hope that eradicating H pylori would curtail the rising use of antiulcer drugs. 2 We describe the long term ef...

We investigated the potential of collagen-genipin sols as biomaterials for treating artificial ulcers following endoscopic submucosal dissection. Collagen sol viscosity increased with condensation, allowing retention on tilted ulcers before gelation and resulting in collagen gel deposition on whole ulcers. The 1.44% collagen sols containing genipin as a crosslinker retained sol fluidity at 23°C...

Prevalence of equine gastric ulcer syndrome in 85 young Thoroughbreds was investigated. The presence of gastric ulcers was confirmed in 27.1% (23/85) of the horses by endoscopic examination. Sixty-two horses without gastric ulcers were allocated randomly to either the treated group (31 horses) or sham-dosed control group (31 horses) in order to investigate the efficacy of omeprazole oral paste ...

BACKGROUND Due to improved care, more and more children born with spina bifida in rural Kenya are surviving into adulthood. This improved survival has led to significant challenges in their lifestyles, especially the need to ensure pressure ulcer prevention and treatment. Malignant degeneration of pressure ulcers in spina bifida patients is very rare. The author describes the clinical presentat...