In the course of attempts to produce mutations in bacteriophage by ultraviolet irradiation of bacteria infected with the phage, we found that suppression of the ability of an infected bacterium to liberate phage required higher doses than either sterilization of noninfected bacteria or inactivation of free phage. . The doses required to suppress phage liberation varied in the course of the inte...

Aerosolized viruses were passed through a high-intensity ultraviolet (UV) cell. This cell consisted of a long cylindrical aluminum tube [diameter, 7 in. (17.7 cm); length, 36 in. (91.4 cm)] with a highly reflective inner surface and a longitudinally extending helical baffle system which directed airborne particles in close proximity to a centrally located UV lamp. After having been passed throu...

Ultraviolet (UV) irradiation or exposure to sunlight are well known but poorly understood predisposing factors of systemic lupus erythematosus (SLE) (Dubois, 1966; Freeman, Knox, and Owens, 1969). It appears from the published literature, that little attention has been paid to what actually occurs when apparently healthy individuals are exposed to UV irradiation. On a molecular level, UV irradi...