BACKGROUND Although "uremic fetor" has long been felt to be diagnostic of renal failure, the compounds exhaled in uremia remain largely unknown so far. The present work investigates whether breath analysis by ion mobility spectrometry can be used for the identification of volatile organic compounds retained in uremia. METHODS Breath analysis was performed in 28 adults with an eGFR ≥ 60 ml/min...

Uraemia, generally extra-renal in origin, is not uncommon in infancy, but comparatively few cases occur in the neonatal period. The following case of extreme uraemia occurring in an infant dying on the eighth day of life is of interest not only on account of the early manifestation of the uraemia, but on account of its degree and the difficulty which has been experienced in establishing the cause.