نتایج جستجو برای: urinary proteomics
تعداد نتایج: 137940 فیلتر نتایج به سال:
Abstract Background and Aims COVID-19 has been a significant public health concern for the last three years; however, not much is known about mechanisms that lead to severe kidney outcomes in patients hospitalized with COVID-19. In this multicenter study, we combine isobaric TMT-tagged urinary proteomics machine learning predict patients. Method Urine samples from two medical centers (Mount Sin...
Omics, referred to a part of biological science that evaluates information, systematically and broadly. Although initially genomics and proteomics have been focused, but along on advances in analytical instruments, potential capabilities of subfields such as Lipidomics recognized, increasingly. Lipidomics studies have been largely able to change the past limited viewpoint to lipids as basic com...
saliva is multifunctional; it is a lubricant for speech, aide for food digestion, and protective against microorganisms. it is voluntarily accessible, composed of proteins and electrolytes, and is ideal for the early detection of a wide range of diseases. because of a complex protein mixture, saliva proteomics has the potential to be a novel approach in the search for protein biomarkers. most s...
Personalized medicine (PM) refers to a set of medical, diagnostic, and therapeutic activities and approaches based on the specific characteristics of each patient chr ('39')s genome. In fact, individual-centered medical approaches are based on personalization, meaning that each person chr ('39')s gene sequence and polymorphisms (SNPs) are different and explain the different courses of urologica...
This Special Issue entitled “Application of Proteomics and Enzyme Technologies in Foods” explores the latest progress perspectives on development application enzyme technologies, proteomics, bioprocessing context food science [...]
BACKGROUND Glucosamine and chondroitin are popular non-vitamin dietary supplements used for osteoarthritis. Long-term use is associated with lower incidence of colorectal and lung cancers and with lower mortality; however, the mechanism underlying these observations is unknown. In vitro and animal studies show that glucosamine and chondroitin inhibit NF-kB, a central mediator of inflammation, b...
Extracellular vesicles (EVs) are microvesicles secreted from various cell types. We aimed to discover a new biomarker for high Gleason score (GS) prostate cancer (PCa) in urinary EVs via quantitative proteomics. EVs were isolated from urine after massage from 18 men (negative biopsy [n = 6], GS 6 PCa [n = 6], or GS 8-9 PCa [n = 6]). EV proteins were labeled with iTRAQ and analyzed by LC-MS/MS. ...
RATIONALE Sleep studies are laborious, expensive, inaccessible, and inconvenient for diagnosing obstructive sleep apnea (OSA) in children. OBJECTIVES To examine whether the urinary proteome uncovers specific clusters that are differentially expressed in the urine of children with OSA. METHODS Two-dimensional differential in-gel electrophoresis (2D-DIGE) and mass spectrometry proteomics foll...
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