UNLABELLED Connections between disease phenotypes and drug effects can be made by identifying commonalities in the associated patterns of differential gene expression. Searchable databases that record the impacts of chemical or genetic perturbations on the transcriptome--here referred to as 'connectivity maps'--permit discovery of such commonalities. We describe two R packages, gCMAP and gCMAPW...

Limitations of current 3D acquisition technology often lead to polygonal meshes exhibiting a number of geometrical and topological defects which prevent them from widespread use. In this paper we present a new method for model repair which takes as input an arbitrary polygonal mesh and outputs a valid two-manifold triangle mesh. Unlike previous work, our method allows users to quickly identify ...

This paper describes a geospatial information system (GIS) that can be used for several mission-critical activities, such as management of risky activities, and urban planning. The main novelty of this system, stands on the ability to analyze and present data inside a 3D media-rich geo-referenced environment. The 3D user interface suggested is based on the idea of interoperable processing units...

This study examines how methods proposed to price traffic in the fixed Internet can be accepted by customers of 3G mobile services. Most previously proposed congestion pricing models are complicated and therefore difficult to be accepted by customers. Simple data pricing methods are needed in today’s 3G networks. A congestion pricing method is proposed only for customers willing to pay more dur...

Atmospheric data analysis is an important area of scientific endeavor, with both government and industrial applications. Our work focuses on clustering particle data acquired via an Aerosol Time-of-Flight Mass Spectrometer (ATOFMS), which is sold and marketed by TSI, Inc. Most papers and software tools developed by the single-particle mass spectrometry community use the ART-2a clustering algori...