To study the appropriateness of phlebotomy for digoxin therapeutic drug monitoring (TDM) in outpatients, we conducted a retrospective chart review, a computer search of all previous TDM testing, and a questionnaire of all outpatients (n = 86) who had serum digoxin determinations between April 10 and April 28, 1992 (585 tests). In patients who took digoxin at the same time daily (40 patients, 30...

BACKGROUND A review update is necessary to document evidence regarding the effectiveness of computer-tailored physical activity and nutrition education. PURPOSE The purpose of this study was to summarize the latest evidence on the effectiveness of computer-tailored physical activity and nutrition education, and to compare the results to the 2006 review. METHODS Databases were searched for r...

The present study was designed to investigate whether absolute work rate (WR) affects Phase I pulmonary oxygen uptake (Vo(2)(p)) duration during moderate-intensity (Mod) exercise and to compare two methods for estimating Phase I Vo(2)(p) duration (P(I-Dur)). Fourteen males (24 ± 5 yr) each completed 4-8 repetitions of Mod transitions from 20 W to 50, 70, 90, 110, and 130 W. P(I-Dur) was identif...

The fac t t ha t sarcomas are induced in rodents by imbedded films of polymers has been established in this l abora to ry (1~-15) and had been conf irmed by a number of o ther invest igators (~, 6, 8, 10, 19). Subsequent studies have shown t h a t this phenomenon is not l imited to films of organic polymers b u t t h a t imbedded meta l foils have the same effect (9, 10, l l ) . This fact , in ...

We contend that the full consequences of managed care for American medicine and health care professionals can be more fully understood if strategies for managing care are identified-in particular, strategies for the administrative oversight of professional decision making. In this paper we apply this perspective to the study of third-party utilization review, making use of a national survey of ...

A nar row, elon gate re gion of an oma lously high meta mor phic grade runs par al lel to Kootenay Lake, in the cen tral part of the Kootenay Arc, south east ern Brit ish Co lum bia. Meta mor phic grade ranges from the chlorite/bi o tite zones on the flanks to the sillimanite+K-feld spar zone in the cen tre of the high. In this pa per, we pres ent a sum mary of struc tural, meta mor phic and ge...

BACKGROUND/AIMS As bacterial resistance to antimicrobial agents has grown due to the increasing use of antimicrobial agents, we sought to evaluate the suitability of ceftriaxone usage (representative of third generation cephalosporins) at 10 university hospitals in Korea. METHODS We prospectively evaluated the appropriateness of antibiotic usage in 400 adult patients who received ceftriaxone ...

In Geographic InfolTnation Systems spatial objects may change their spatiallocation and/or shapes over time. Query processing of such spatiotemporal objects consists of spatial query conditions and temporal query conditions. Dur study focuses on representing the spatiotemporal monitoring of a polygonal object and aims at developing an efficient data structure supporting queries and operations t...

Feeding low concentrations of DDGS early in the nursery period does not help to maintain growth performance when high concentrations of DDGS are incorporated in the diets during the late nursery period. Summary The objective of this experiment was to evaluate growth performance of weanlingpigs introduced to low concentrations (5%) of DDGS duringphase 2 of the nursery period followed by high con...

T h e third c o m p o n e n t of complemen t (C) ~ has a central role in the activation of both the classical and al ternat ive pathways. C3 also has a variety o f di f ferent functions that are expressed e i ther a f ter C3 activation or dur ing the normal b reakdown o f the molecule. These functions of C3 are dependen t upon the exposure within C3 o f binding sites for o ther se rum proteins ...