Objective The aim of the present randomized placebo-controlled single-center study was to assess efficacy and safety a new vaginal gel (Meclon Idra - Alfasigma) in treatment vulvovaginal atrophy (VVA). is composed sea buckthorn (Hippophaë rhamnoides) oil, aloe vera, 18?-glycyrrhetic acid, hyaluronic acid glycogen. assessed whether can reduce VVA symptoms (vaginal dryness, itching, burning sensa...

BACKGROUND Tamoxifen, a selective estrogen receptor modulator with both estrogenic and anti-estrogenic activity, is widely used as adjuvant therapy in breast cancer patients. Treatment with tamoxifen is associated with sexual side effects, such as increased vaginal dryness and pain/discomfort during sexual activity. There have been limited investigations of the effect of tamoxifen on estrogen-d...

Address for Correspondence: Cihat Ünlü, Women’s Health Clinic, Abdi Ipekci Caddesi 2/7, 34357 Nişantaşı, İstanbul, Turkey Phone: +90 212 241 45 45 Fax: +90 212 241 44 08 e.mail: [email protected] ©Copyright 2011 by the Turkish-German Gynecological Education and Research Foundation Available online at www.jtgga.org doi:10.5152/jtgga.2011.57 To maintain a healthy vaginal ecosystem or to restore an...

BACKGROUND In women with cancer-related hysterectomy, the vaginal vault cytology has a low efficacy - when performed by conventional methods - for the early detection of vaginal recurrence. The amount of exfoliated cells collected is generally low because of atrophy, and the vaginal vault corners can be so narrow that the commonly used Ayres spatula cannot often penetrate deeply into them. This...