In this study, we investigated the potential protective effects of Valeriana officinalis (V. officinalis) against the toxicity induced by rotenone in Drosophila melanogaster (D. melanogaster). Adult wild-type flies were concomitantly exposed to rotenone (500 μM) and V. officinalis aqueous extract (10mg/mL) in the food during 7 days. Rotenone-fed flies had a worse performance in the negative geo...

Medicinal plants used during the plague described in Herbarium of Simon Syrenius (1613) Before effective methods treatment and prevention infections all other infectious diseases were known, attempts made to treat them with natural means. The blight, among others considered following plants: angelica (Angelica archangelica), valerian (Valeriana officinalis), pimpinella, (Pimpinella sp.) common ...

The ethanolic crude extract of Valeriana wallichii rhizome (VwR.Cr) was studied in vitro for its possible antispasmodic activity to rationalize some of its folkloric uses. Segments of 2-3 cm long of rabbit jejunum preparations were mounted in Tyrode’s solution and aerated with 95% oxygen in carbon dioxide. Isotonic responses were measured on Bioscience oscillograph. VwR.Cr caused a dose-depende...

The ethanolic crude extract of Valeriana wallichii rhizome (VwR.Cr) was studied in vitro for its possible antispasmodic activity to rationalize some of its folkloric uses. Segments of 2-3 cm long of rabbit jejunum preparations were mounted in Tyrode’s solution and aerated with 95% oxygen in carbon dioxide. Isotonic responses were measured on Bioscience oscillograph. VwR.Cr caused a dose-depende...

The volatile constituents from roots of Valeriana officinalis L. were investigated using GC and GC/MS methods. Valerianae radix samples were obtained from retail pharmacies or cultivated in Estonia. The roots of five V. officinalis samples yielded 0.28–1.16% essential oil in the cut drug, which usually corresponded (four samples) to the European Pharmacopeia standard (0.3%). The basic oil compo...