INTRODUCTION Vascular endothelial growth factor is thought to be an important angiogenic factor involved in tumor growth, progression, and metastasis. OBJECTIVE The present study evaluated the relation between tissue expression, serum and salivary levels of vascular endothelial growth factor in head and neck squamous cell carcinomas, and their correlation with clinicopathologic features. ME...

Aflibercept (Eylea) injection (CPB 0701 Vascular Endothelial Growth Factor Inhibitors for Ocular Indications) Bevacizumab (Avastin) injection (CPB 0685 Bevacizumab (Avastin)) Pegaptanib sodium (Macugen) injection (CPB 0701 Vascular Endothelial Growth Factor Inhibitors for Ocular Indications) Photodynamic therapy (PDT) with light-activated verteporfin (CPB 0594 Visudyne (Verteporfin) Photodynami...

BACKGROUND AND PURPOSE Vascular endothelial growth factor is a well-known tumor-specific biomarker that mediates angiogenesis in glioblastoma via hypoxia-dependent mechanisms. Our aim was to investigate the correlation of clinical characteristics, radiologic features, and vascular endothelial growth factor expression with survival outcomes in patients with glioblastoma. MATERIALS AND METHODS ...

OBJECTIVE To assess whether an erythematous eruption in the vicinity of or distant from a melanoma lesion might be related to the vascular endothelial growth factor, the platelet-derived endothelial cell growth factor, or both. METHODS Biopsy specimens from 13 patients with primary melanoma, 6 of whom had erythematous eruptions and 7 who did not, were studied by immunohistochemistry for the e...

Background: Nasal inflammatory disorders such as chronic rhinosinusitis and nasal polyp are among the most prevalent complications with high socioeconomic costs. Vascular Endothelial Growth Factor (VEGF) plays a key role in angiogenesis and cell proliferation. In the present study the effect of VEGF on the development and prognosis of chronic rhinosinusitis and nasal p...

OBJECTIVE Angiogenesis is one of the crucial steps in various solid tumor growth and metastasis. However, there are limited data regarding the clinical and prognostic significance of serum vascular endothelial growth factor levels per platelet count in unresectable advanced gastric cancer compared with early gastric cancer and healthy volunteers. METHODS A total of 181 gastric cancer patients...

Procyanidins are a family of plant metabolites that have been suggested to mitigate osteoarthritis pathogenesis in mice. However, the underlying mechanism is largely unknown. This study aimed to determine whether procyanidins mitigate traumatic injury-induced osteoarthritis (OA) disease progression, and whether procyanidins exert a chondroprotective effect by, at least in part, suppressing vasc...