نتایج جستجو برای: vascular smooth muscle cells

تعداد نتایج: 1847951  

Journal: :Hypertension 2013
Matthew A Sparks Natalia A Makhanova Robert C Griffiths John N Snouwaert Beverly H Koller Thomas M Coffman

The prostanoid thromboxane A2 has been implicated to contribute to the pathogenesis of many cardiovascular diseases, including hypertension. To study the role of vascular thromboxane-prostanoid (TP) receptors in blood pressure regulation, we generated mice with cell-specific deletion of TP receptors in smooth muscle using Cre/Loxp technology. We crossed the KISM22α-Cre transgenic mouse line exp...

Journal: :Cardiovascular research 2011
Andrea Olschewski

Vascular smooth muscle cells are important for the structural integrity of the tunica media, but they are also central to vascular remodelling in response to injury. Although they are highly differentiated cells with the ability to regulate vascular tone and synthesize extracellular matrix, smooth muscle cells are also very plastic cells. This enables them to switch from a contractile to an inv...

Journal: : 2021

In this review, the aim is to discuss pathological development of vascular calcification including a brief description arterial wall structure and function, atherosclerosis, highlighting normal physiological with particular emphasis on their common characteristics, critically review recent findings implicating role smooth muscle cells in pathogenesis process microRNAs regulation these phenotype...

Journal: :Circulation Research 1973

Journal: :Arteriosclerosis, Thrombosis, and Vascular Biology 2002

Journal: :Arteriosclerosis, Thrombosis, and Vascular Biology 1999

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