This work investigates a novel turbocharged EGR system installed on a laboratory marine engine. A problem of recirculation of high and stable portion of exhaust gas in marine engines is addressed. Although conventional EGR systems have been extensively presented in research papers, the setup shown in this paper has not been well described. Therefore, we develop a mean-value model of the system ...

Banks, Mark F., Evgenia V. Gerasimovskaya, Doug A. Tucker, Maria G. Frid, Todd C. Carpenter, and Kurt R. Stenmark. Egr-1 antisense oligonucleotides inhibit hypoxia-induced proliferation of pulmonary artery adventitial fibroblasts. J Appl Physiol 98: 732–738, 2005. First published October 8, 2004; doi:10.1152/japplphysiol. 00821.2004.—In most mammalian species, chronic exposure to hypoxia leads ...

Combustion, performance and emission were studied for DI diesel engine fuelled with DMM/diesel fuel blends for DMM content from 0 to 50%. Results showed that, for diesel engine with fuel supply system and combustion system unchanged, with increased DMM percentage, thermal efficiency slightly increases; smoke and CO emissions decrease, NOx remains almost unchanged while HC increases a little; fo...

One strategy to decrease the amount of oxides of nitrogen formed and emitted from certain combustion devices, such as the internal combustion engine, is to recirculate and introduce a portion of the unburned product gases with the air and fuel. The effect of the re-circulated gases is to decrease the maximum temperatures in the flame zone, and hence decrease NOx formation. However, dilution of ...

Previous research has shown that nitric oxide signalling in the lateral nucleus of the amygdala is required for the consolidation of Pavlovian conditioned fear. Given the evidence that nitric oxide can act as a retrograde signalling molecule in in vitro models of memory consolidation the question arises whether this is also occurring within behavioural memory models? Using auditory fear conditi...

Aging is associated with a large number of both phenotypic and molecular changes, but for most of these, it is not known whether these changes are detrimental, neutral, or protective. We have identified a conserved Caenorhabditis elegans GATA transcription factor/MTA-1 homolog egr-1 (lin-40) that extends lifespan and promotes resistance to heat and UV stress when overexpressed. Expression of eg...

Early growth response factor-1 (EGR-1) is an immediate early gene, which is rapidly activated in quiescent cells by mitogens or in postmitotic neurons after depolarization. EGR-1 has been involved in diverse biological functions such as cell growth, differentiation and apoptosis. Here we report that enforced expression of the EGR-1 gene induces apoptosis, as determined by flow cytometry and ter...

Interleukin-1 (IL-1) is a growth arrest signal for diverse human tumor cell lines. We report here that the action of this cytokine in melanoma cells is associated with induction of EGR-1, a zinc finger protein that activates gene transcription. Both growth arrest and EGR-1 are induced via the type I receptor of IL-1. To determine the role of EGR-1 in IL-1 action in melanoma cells, we used a chi...