Primary progressive aphasia (PPA) is a syndrome characterized by a progressive language deficit without other dementia features for at least two years (). Other deficits that are likely to co-exist with aphasia, such as apraxia, have only been investigated in a few case studies and only at a rudimentary level for the most part. In this study we investigate the frequency and severity of apraxic ...

Objective: To evaluate apraxia in healthy elderly and in patients diagnosed with Alzheimer’s disease (AD) and Mild cognitive impairment (MCI). Methods: We evaluated 136 subjects with an average age of 75.74 years (minimum 60 years old, maximum 92 years old) and average schooling of 9 years (minimum of 7 and a maximum of 12 years), using the Mini-Mental State examination (MMSE), Cambridge Cognit...

Ideomotor limb apraxia is a classic neurological disorder manifesting as a breakdown in co-ordinated limb control with spatiotemporal deficits. We employed kinematic analyses of simple aiming movements in left hemisphere-damaged patients with and without limb apraxia and a normal control group to examine preprogramming and response implementation deficits in apraxia. Damage to the frontal and p...

Ocular motor apraxia has been reported in bilateral frontoparietal lesions. We report a case of ocular motor apraxia after bilateral striatal infarctions. The patient had impaired voluntary saccades and smooth pursuits in the vertical and horizontal planes with an intact vestibulo-ocular reflex. Magnetic resonance imaging showed an old left putaminal infarction and an acute infarction in the ri...

A systematic neuropsychological assessment technique is described for use with severely physically disabled individuals, possibly with combined motor and cognitive disorders. Target neurological conditions may be, e.g., an incomplete locked-in state, a minimally conscious state, or severe combinations of paralysis, agnosia, and apraxia. Neuropsychological assessment in these patients is difficu...

Constructional apraxia refers to the inability of patients to copy accurately drawings or three-dimensional constructions. It is a common disorder after right parietal stroke, often persisting after initial problems such as visuospatial neglect have resolved. However, there has been very little experimental investigation regarding mechanisms that might contribute to the syndrome. Here, we exami...

Apraxia is a symptom on the border between cognition and motor control. It is predominantly caused by left brain damage and frequently accompanied by aphasia. Theories of apraxia have been dominated by a model of the conversion of mental images into motor commands proposed more than 100 years ago by the German psychiatrist Hugo Liepmann and revived for modern cognitive neurology by Norman Gesch...

Apraxia is a symptom on the border between cognition and motor control. It is predominantly caused by left brain damage and frequently accompanied by aphasia. Theories of apraxia have been dominated by a model of the conversion of mental images into motor commands proposed more than 100 years ago by the German psychiatrist Hugo Liepmann and revived for modern cognitive neurology by Norman Gesch...