نتایج جستجو برای: viper venoms
تعداد نتایج: 6703 فیلتر نتایج به سال:
Lupus anticoagulant (LAC) testing is important for evaluating patients with antiphospholipid syndromes and hypercoagulable states. We reviewed results of proficiency testing challenges (n = 5) distributed by the North American Specialized Coagulation Laboratory Association to examine LAC testing performed by participating laboratories. The activated partial thromboplastin time (APTT) and dilute...
The Gaboon viper has acquired an impressive reputation which is at least partly unfounded. This handsome animal with such striking features is undoubtedly docile which accounts for the very low incidence of bite amongst humans. There are only six detailed clinical reports on the effect of bite and these are summarized in the review. The viper does indeed produce prodigious amounts of venom, but...
Introduction: Thrombosis is one of the leading causes mortality worldwide. Thrombolytic agents are used to reduce this burden. Studies pointed out that certain proteins in venom several snake species may have potential thrombolytic properties. Trimeresurus flavomaculatus, known as Philippine pit viper, found along damp localities Philippines. Venoms closely related been shown exhibit effects vi...
Viper venoms from the Elapidae, Hydrophiidae, Atractaspididae, Viperidae and Colubridae families contain at least 25 separate classes of biologically active compounds [1]. Nomenclature standardization of these molecules by structure and function have been reported for prothrombin activators [2; 3]. No such agreement has been made for the nomenclature and classification of disintegrins which, fo...
Background Snakebite in India results over 58,000 fatalities and a vast number of morbidities annually. The majority these clinically severe envenomings are attributed to Russell’s viper ( Daboia russelii ), which has near pan-India distribution. Unfortunately, despite its medical significance, the influence biogeography on composition potency venom from disparate D . populations, repercussions...
Medically important cases of snakebite in Europe are predominately caused by European vipers of the genus Vipera. The mainstay of snakebite therapy is polyclonal antibody therapy, referred to as antivenom. Here we investigate the capability of the monospecific V. berus antivenom, ViperaTAb®, to cross-react with, and neutralise lethality induced by, a variety of European vipers. Using ELISA and ...
Central and South American pitvipers, belonging to the genera Bothrops and Bothriechis, have independently evolved arboreal tendencies. Little is known regarding the composition and activity of their venoms. In order to close this knowledge gap, venom proteomics and toxin activity of species of Bothriechis, and Bothrops (including Bothriopsis) were investigated through established analytical me...
BACKGROUND Snake venom is a potentially lethal and complex mixture of hundreds of functionally diverse proteins that are difficult to purify and hence difficult to characterize. These difficulties have inhibited the development of toxin-targeted therapy, and conventional antivenom is still generated from the sera of horses or sheep immunized with whole venom. Although life-saving, antivenoms co...
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