PURPOSE To explore the attachments of the posterior zonule and vitreous in relation to accommodation and presbyopia in monkeys and humans. METHODS Novel scanning electron microscopy (SEM) and ultrasound biomicroscopy (UBM) techniques were used to visualize the anterior, intermediate, and posterior vitreous zonule and their connections to the ciliary body, vitreous membrane, lens capsule, and ...

For eyes with diabetic retinopathy which require vitreous surgery and pan-retinal photocoagulation (PRP), pre-treatment of PRP before vitreous surgery reduce the activity of diabetic retinopathy, however sometimes cause macular edema leading to visual disturbance. Some cytokines in the vitreous increase in eyes with diabetic macular edema, thus the relationship between PRP and vitreous cytokine...

Swift, P. G. F., Worthy, E., and Emery, J. L. (1974). Archives of Disease in Childhood, 49, 680. Biochemical state of the vitreous humour of infants at necropsy. Biochemical analysis of the vitreous humour in 80 infants brought to necropsy, including 18 in whom terminal plasma levels were known, indicates that sodium and urea levels closely reflect ante-mortem plasma values. With increasing tim...

PURPOSE Pharmacologic vitreolysis is a promising new therapy to improve vitreoretinal surgery and, ultimately, prevent disease by mitigating the contribution of vitreous to retinopathy. The mechanism of action of the agents being developed for pharmacologic vitreolysis remains unclear. The experiments in this thesis test the hypothesis that pharmacologic vitreolysis agents break down vitreous m...

To determine the mechanisms of vitreous liquefaction following vitreous hemorrhage, we investigated the effects of the free radicals produced by a bilirubin-sensitized photochemical reaction on collagen and hyaluronic acid (HA). Bovine vitreous collagen and HA were irradiated by visible light in the presence of bilirubin, which is produced from the degradation of hemoglobin, as a photosensitize...

OBJECTIVES To measure the concentrations of vancomycin in the vitreous of patients with postoperative endophthalmitis after administration of 1 g of vancomycin hydrochloride intravenously and injection of 1 mg of vancomycin hydrochloride into the vitreous, and to determine whether these concentrations are adequate for treatment of gram-positive infections. METHODS Patients with acute postoper...

Dear Editor, Rupture of the posterior capsule and prolapse of the vit-reous body are relatively common complications of cataract surgery. When posterior capsule rupture (PCR) occurs, the vitreous body prolapsed into anterior chamber should be removed completely. However, the surgical procedure to remove the vitreous body is difficult and troublesome because the vitreous structure is transparent...

Human being gets about 90% of the information via visual sense[1,2]. Therefore, it is generally thought that the sight greatly influences the QOL (quality of life) of people. It is a vitreous body to take an important role to obtain visual information[3]. The vitreous body, which holds about 80% of the volume of the eyeball, is located between the crystalline lens, a ciliary body and the retina...

AIMS To ascertain whether measurement of the vitreous fluid levels of vascular endothelial growth factor (VEGF) or angiotensin II (Ang II) could predict the outcome of vitreous surgery in patients with proliferative diabetic retinopathy (PDR). METHODS A prospective observational case study was performed in 61 consecutive patients (61 eyes) with PDR who underwent vitreoretinal surgery. Vitreou...

OBJECTIVE Diabetic retinopathy is associated with progressive retinal capillary activation and proliferation, leading to vision impairment and blindness. Microparticles are submicron membrane vesicles with biological activities, released following cell activation or apoptosis. We tested the hypothesis that proangiogenic microparticles accumulate in vitreous fluid in diabetic retinopathy. RESE...