Despite the fact that specific prophylaxis agents have already been widely introduced into medical practice in all countries of world, and antiviral drugs are being developed undergoing first stages clinical trials, SARS-CoV-2 continues to spread human population. In this regard, an urgent problem today is expansion arsenal effective disinfectants antiseptics, action which would be aimed at rap...

Objective: Brucellosis is a serious zoonotic infection worldwide. To date, vaccination the most effective measure against brucellosis. This study was aimed at obtaining vaccine strain that has high protective efficacy and low toxicity, allows to be differentiated from infection. Methods: Using homologous recombination, we constructed double gene-deletion Brucella MB6 ?bp26?wboA (RM6) evaluated ...