Introduction Constant-time point-resolved spectroscopy (CT-PRESS) [1] is a single voxel technique that simplifies the spectral pattern and permits the detection of Jcoupled resonances with high signal-to-noise ratio by using effective homonuclear decoupling [2]. The technique relies on non-selective refocusing, i.e., effective homonuclear decoupling is only achieved if the RF pulses refocus all...

We propose a method for reconstruction of human brain states directly from functional neuroimaging data. The method extends the traditional multivariate regression analysis of discretized fMRI data to the domain of stochastic functional measurements, facilitating evaluation of brain responses to complex stimuli and boosting the power of functional imaging. The method searches for sets of voxel ...

In vivo magnetic resonance spectroscopic imaging of the prostate using single-voxel and multivoxel two-dimensional (2D) J-resolved sequences is investigated at a main magnetic field strength of 3 T. Citrate, an important metabolite often used to aid the detection of prostate cancer in magnetic resonance spectroscopic exams, can be reliably detected along with the other metabolites using this me...

This paper presents a supervised voxel classification method for segmentation of the caudate nucleus from brain MRI images. Supervised voxel classification is a general pattern recognition technique. In this application general spatial and local structure features extracted from image voxels were used together with a k-nearest neighbor classifier. The trained classifier has been applied to diff...

This paper presents a discriminative model of multivariate pattern classification, based on functional magnetic resonance imaging (fMRI) and anatomical template. As a measure of brain function, Regional homogeneity (ReHo) is calculated voxel by voxel, and then a widely used anatomical template is applied on ReHo map to parcelate it into 116 brain regions. The mean and standard deviation of ReHo...

To what extent do all brains work alike during natural conditions? We explored this question by letting five subjects freely view half an hour of a popular movie while undergoing functional brain imaging. Applying an unbiased analysis in which spatiotemporal activity patterns in one brain were used to "model" activity in another brain, we found a striking level of voxel-by-voxel synchronization...

How does the human motor system encode our incredibly diverse motor repertoire in an efficient manner? One possible way of encoding movements efficiently is to represent them according to their shape/trajectory without regard to their size, by using neural populations that are invariant across scale. To examine this hypothesis, we recorded movement kinematics and functional magnetic resonance i...

INTRODUCTION: One important limitation of DTI is its inability to resolve multiple crossing fibers within a voxel. Diffusion Spectrum Imaging (DSI) allows such resolution by Nyquist sampling a 3D q-space[1] for each voxel. The water displacement probability (“propagator”) corresponds to the Fourier transform of the MR signal as a function of q r . This high dimensionality imposes a trade-off be...