Approximately 80% of psoriatic individuals experience pruritus, of varying intensity. This study evaluated the frequency of vulvar itching and burning and its influence on well-being in women with psoriasis. A total of 93 women were included in the study. Psoriasis severity was assessed according to the Psoriasis Area and Severity Index, the intensity of vulvar discomfort by visual analogue sca...

Object: To determine if vulvar melanosis progressed to melanoma over a period of 20 years or more. Methods: In 2010 the hospital records from the Royal Brisbane Hospital Vulvar Clinic between 1976 and 1988 were reviewed and cross checked with the state wide Queensland Centre for Gynaecological Cancer (QCGC) data base to determine if any patient had been lost to follow up and subsequently develo...

Vulvar lymphedema is an uncommon and disabling side-effect of pelvic lymphadenectomy and pelvic radiotherapeutic treatment for invasive genital cancer. Lymphorrhea, a complication of lymphedema, may be extremely distressing for patients due to the requirement to wear sanitary towels and as the pain and loss of elasticity of the vulvar skin and mucosa can cause discomfort during coitus. Surgical...

Vulvar leiomyomas are extremely rare smooth muscle tumors that easily mistaken for other lesions, as the differential diagnosis must consider a wide spectrum of benign and malignant lesions. We present case 52-year-old woman with three-year history progressive abdominal distension pain an enlarging vulvar mass distorting labia majora causing gait disturbance. Imaging confirmed enormous pelvic o...

MiR-223-5p has been previously mentioned to be associated with tumor metastasis in HPV negative vulvar carcinomas, such as in several other tumor types. In the present study, we hypothesized that this microRNA would be important in vulvar cancer carcinogenesis and progression. To investigate this, we artificially mimicked miR-223-5p expression in a cell line derived from lymph node metastasis o...

Syringoma is a benign eccrine sweat gland tumour affecting mostly females at puberty as multiple soft papules usually 1-2 mm in diameter. The sites of predilection are lower eyelids, cheeks. Syringoma of the vulva is a rare disorder. Only few cases have been reported in the literature. We report here a case of 46-year-old female who presented to gynecology department with vulvar papules associa...

A 67-year-old woman who was presented to the gynecologist with a two-month history of heavy vaginal bleeding, after an excisional biopsy of vulvar mass, was diagnosed with the right colon adenocarcinoma metachronous metastasis to the vulva. Pathological examination preliminarily revealed by primary adenosquamous carcinoma of vulva. The original submitting pathologist and gynecologist were conta...

Primary vulvar adenocarcinomas are very rare. We describe the rare case of primary vulvar apocrine adenocarcinoma, a histologically rare subtype of vulvar adenocarcinoma. A 57-year-old Japanese woman presented with an enlarging vulvar mass. A dark-red, hemorrhagic, ulcerated tumor was on the right side of the anterior labial commissure measuring approximately 3.5 × 3.5 cm. Preoperative biopsy s...

Pigmented vulvar lesions are present in approximately 1 in 10 women and include melanocytic and nonmelanocytic proliferations. Vulvar nevi, melanosis, and melanoma are particularly challenging because of the similarity of their clinical and/or histopathological presentation. As a result, they are often difficult to diagnose, may result in patient and physician anxiety, and can lead to unneeded,...

Vulvar cancer is the fourth most common gynecologic malignancy, accounting for 5 to 8% of all female genital tract malignancies (Stehman, 2007). It affects 4850 new patients annually in the United States (Siegel, Ma, Zou, & Jemal, 2014) and 3190 new patients in Germany (Kaatsch et al., 2013), with an annual estimated death rate of 1030 and 750, respectively, in the two countries (Kaatsch et al....