The computational sampling of rare, large-scale, conformational transitions in proteins is a well appreciated challenge-for which a number of potentially efficient path-sampling methodologies have been proposed. Here, we study a large-scale transition in a united-residue model of calmodulin using the "weighted ensemble" (WE) approach of Huber and Kim. Because of the model's relative simplicity,...

A lonesum matrix is a (0, 1)-matrix uniquely determined by its column and row sums, and the sum of its all entries is called the “weight” of it. The generating function of numbers of weighted lonesum matrices of each weight is given. A certain explicit formula for the number of weighted lonesum matrices is also proved.

in this paper, we considered composition operators on weighted hilbert spaces of analytic functions and  observed that a formula for the  essential norm, gives a hilbert-schmidt characterization and characterizes the membership in schatten-class for these operators. also, closed range composition operators  are investigated.

in this paper, we consider scheduling of project networks under minimization of total weighted resource tardiness penalty costs. in this problem, we assume constrained resources are renewable and limited to very costly machines and tools which are also used in other projects and are not accessible in all periods of time of a project. in other words, there is a dictated ready date as well as a d...

introduction contrast-enhanced fluid-attenuated inversion recovery (flair) is one of the mri sequences that can be used for detection and evaluation of pathological changes in the brain. in this work, we have studied the effect of different echo times (te) on the maximum relationship between signal intensity and concentration of the contrast agent using the flair sequence. materials and methods...

let g be a locally compact group, and let ω be a weight on g. we show that the weightedmeasure algebra m(g,ω) is amenable if and only if g is a discrete, amenable group andsup{ω(g) ω(g−1) : g ∈ g} < ∞, where ω(g) ≥ 1 (g ∈ g) .