introduction: multiple sclerosis (ms) is a demyelinating disease of the central nervous system (cns), affecting mostly young people at a mean age of 30 years. magnetic resonance imaging (mri) is one of the most specific and sensitive methods in diagnosing and detecting the evolution of multiple sclerosis disease. but it does not have the ability to differentiate between distinct histopathologic...

Magnetic resonance imaging (MRI) is playing an increasing role in the assessment of patients with liver disease due to its high soft tissue resolution, lack of ionizing radiation and ability to provide functional data. There are various types of diseases in the liver. So, to identify these diseases and to get a clear image of the damaged part various imaging techniques are used mainly Sonograph...

BACKGROUND AND PURPOSE The perfusion-weighted imaging (PWI)-diffusion-weighted imaging (DWI) mismatch paradigm is widely used in stroke imaging studies. Arterial spin labeling (ASL) is an alternative perfusion method that does not require contrast. This study compares the agreement of ASL-DWI and PWI-DWI mismatch classification in patients with stroke. METHODS This was a retrospective study d...

Diffusion-weighted MRI (DWI) by means of apparent diffusion coefficient (ADC) calculation can be used for in vivo quantification of the combined effects of capillary perfusion and diffusion. With the advent of echoplanar imaging (EPI), DWI of the abdomen has become possible with fast imaging times minimizing the effect of gross physiologic motion from respiration and cardiac movement. Several s...

Magnetic resonance imaging (MRI) can be used to monitor pathological changes in Alzheimer's disease (AD). The objective of this longitudinal study was to assess the effects of progressive amyloid-related pathology on multiple MRI parameters in transgenic arcAβ mice, a mouse model of cerebral amyloidosis. Diffusion-weighted imaging (DWI), T1-mapping and quantitative susceptibility mapping (QSM),...

BACKGROUND AND PURPOSE MRI has been increasingly used in the evaluation of acute stroke patients. However, MRI must be able to detect early hemorrhage to be the only imaging screen used before treatment such as thrombolysis. Susceptibility-weighted imaging, an echo-planar T2* sequence, can show intracerebral hemorrhage (ICH) in patients imaged between 2.5 and 5 hours from symptom onset. It is u...

INTRODUCTION Gradient echo (GRE) imaging has a wide range of clinically useful applications. In particular, GRE imaging is frequently used in the clinic for anatomical/structural imaging and imaging dynamics for diseases that span all organ systems and numerous pathologies. In general, an advantage of GRE imaging is the fact that it is regarded as “fast” owing to the generally short repetition ...

Assessment of the integrity of the articular cartilage is considered key for the early diagnosis of osteoarthritis (OA). Diffusion-weighted imaging and diffusion tensor imaging have potential as biomarkers for cartilage composition and structure. The value of diffusion to detect compositional and structural changes in the cartilage matrix has been shown in ex vivo experiments for several years....

BACKGROUND AND PURPOSE We investigated 2 methods of measuring MR imaging perfusion-diffusion mismatch to determine whether reliability is improved by direct measurement on a single, blended map. MATERIALS AND METHODS Image software was used for measurement of lesion volumes from diffusion-weighted images (DWI) and mean transit time (MTT) calculated from perfusion-weighted (PWI) images on 64 p...

Noise in MR image data increases the mean signal intensity of image regions due to the usually performed magnitude reconstruction. Diffusion-weighted imaging (DWI) is especially affected by high noise levels for several reasons, and a decreasing SNR at increasing diffusion weighting causes systematic errors when calculating apparent diffusion coefficients (ADCs). Two different methods are prese...