Purpose: To characterize some preformulation properties of aqueous stem bark extract of Bridelia ferruginea Benth (Euphorbiaceae) (BF). Methods: The stem bark was extracted by maceration in hot distilled water. Two batches of granules containing the extract were prepared by wet granulation using maize starch, polyvinylpyrrolidone (PVP), Avicel PH-101, magnesium stearate, acacia and lactose as e...

With the development in egocentric vision, skill measurement has been recently proposed as a novel topic in this emerging field. In this report, we record the the experimenter’s first-person videos in Wet labratories (wetlab), and measure his/her operative skills. Specifically, given the videos of expert and amateur, we analyze their head motions, hands motions, eye-hand coordinations and key-m...

Objective: The objective of the study was to prepare and evaluate formulation granules effervescent from kirinyuh mareme leaves as an antioxidant.
 Methods: method making with wet granulation method. used for granules, meanwhile, evaluations included organoleptic tests, water content, solubility time, pH preparation, compressibility, flow time angle repose antioxidant activity.
 Resul...

The object of the study was to formulate and evaluate Aceclofenac orodispersible tablets (ODT) by wet granulation method using different super disintegrants in different concentrations. Orodispersible tablets produce rapid dissolution of drug and absorption thereby producing rapid onset of action. Five batches (AFD1, AFD2, AFD3, AFD4, AFD5) of Aceclofenac orodispersible tablets were prepared an...

The aqueous extract of C. papaya fruit (100 mg kg(-1) day(-1) for 10 days) was evaluated for its wound healing activity in streptozotocin-induced diabetic rats using excision and dead space wound models. Extract-treated animals exhibited 77% reduction in the wound area when compared to controls which was 59%. The extract treated wounds were found to epithelize faster as compared to controls. Th...

Possibilities of application of non-ionic surfactants of Rofam type as solubilizers for piroxicam poorly dissolved in water were assessed. Homologous series of Rofams containing oxyethylene segments from 3 to 18 were used in the study. Tablet formulation was made by wet granulation technique using these surfactants in order to improve drug dissolution properties. Influence of both quantity and ...

We report that a variety of ternary particle/liquid/liquid mixtures heavily aggregate or separate completely if (1) the particles are fully or almost fully wetted by one fluid, and (2) if the wetting fluid volume fraction is comparable to the particle volume fraction. Aggregation and separation do not happen if the particles are partially wetted by both fluids, in which case Pickering emulsions...

In the present study an attempt was made to formulate and evaluate Calcium and Vitamin K3 tablet using wet granulation technique incorporating various Excipients like Starch Powder, Starch Paste, Magnesium Sterate, Aerosil, Talc, Lactose, Vitamin K Liquid form and Water. The Formulated tablets were evaluated for different physicochemical properties like rheological properties, weight variation,...

Trimetazidine dihydrochloride, a cellular antiischemic agent indicated in the management and prophylaxis of angina pectoris is given as 20 mg thrice daily in the conventional dosage regimen. The purpose of the present study was to formulate and evaluate twice a day extended release tablets containing 30 mg trimetazidine dihydrochloride. The method developed to formulate these extended release t...

Shankha Bhasma is a popular Ayurvedic formulation which is used in hyperacidity, indigestion, ulcerative dyspepsia and other acid peptic disorders. The dosage uniformity and patient compliance can be increased and adultration can be decreased in ayurvedic powders by formulating them into tablets. The aim of the present work is to develop and evaluate Shankha Bhasma tablets using starch and acac...