Investigation of protein self-assembly processes is important for understanding the growth functional proteins as well disease-causing amyloids. Inside cells, intrinsic molecular fluctuations are so high that they cast doubt on validity deterministic rate-equation approach. Furthermore, environments inside cells often crowded with other macromolecules, volume fractions crowders 40%. We have dev...

Background and Aims: considering difficulties in usual laboratory methods in detection of viral infections, improved DNA-based diagnostic techniques are more reliable. Loop mediated isothermal amplification method (LAMP) is a nucleic acid amplification method that amplifies DNA using six primers which has been developed to diagnose viruses as a rapid and high efficiency test. In this study, the...

Graphene sheets are combined of Honeycombs lattice carbon-carbon bonds which have high natural frequencies, high strength, and high conductivity. Due to important applications of the graphene sheets particularly at higher frequencies, the study of their dynamic behavior is important in this frequency range. From Molecular Dynamics (MD) point of view as the dimensions of graphene sheet incline, ...

Gap junction intercellular communication/Cell killing/Potentially lethal damage repair/DNA damage/ Linear energy transfer of space radiation. Understanding the mechanisms that underlay the biological effects of particulate radiations is essential for space exploration and for radiotherapy. Here, we investigated the role of gap junction intercellular communication (GJIC) in modulating harmful ef...

The performance of an inexpensive, ensemblebased optimal interpolation (EnOI) scheme that uses a stationary ensemble of model anomalies to approximate forecast error covariances, is compared with that of an ensemble Kalman filter (EnKF). The model to which the methods are applied is a pair of “perfect”, one-dimensional, linear advection equations for two related variables. While EnOI is sub-opt...