Texture perception is studied here in a physical model of the rat whisker system consisting of a robot equipped with a biomimetic vibrissal sensor. Investigations of whisker motion in rodents have led to several explanations for texture discrimination, such as resonance or stick-slips. Meanwhile, electrophysiological studies of decision-making in monkeys have suggested a neural mechanism of evi...

Active sensing requires the brain to distinguish signals produced by external inputs from those generated by the animal's own movements. Because the rodent whisker musculature lacks proprioceptors, we asked whether trigeminal ganglion neurons encode the kinematics of the rat's own whisker movements in air. By examining the role of kinematics, we have extended previous findings showing that many...

Corticothalamic (CT) projections are approximately 10 times more numerous than thalamocortical projections, yet their function in sensory processing is poorly understood. In particular, the functional significance of the topographic precision of CT feedback is unknown. We addressed these issues in the rodent somatosensory whisker/barrel system by deflecting individual whiskers and pharmacologic...

Most corticothalamic (CT) neurons in somatosensory cortex are silent in lightly anesthetized and even awake animals, making it difficult to investigate CT function and the underlying circuitry. Here we use juxtasomal recording and stimulation techniques to probe subthreshold response properties of antidromically identified CT neurons in the rat whisker/barrel system. When neuronal firing is fac...

Functional maps in the cerebral cortex reorganize in response to changes in experience, but the synaptic underpinnings remain uncertain. Here, we demonstrate that layer (L) 2/3 pyramidal cell synapses in mouse barrel cortex can be potentiated upon pairing of whisker-evoked postsynaptic potentials (PSPs) with action potentials (APs). This spike-timing-dependent long-term potentiation (STD-LTP) w...

The project described in this paper has the aim of demonstrating that whisker sensors can be used as a rapid and effective form of robot sensing. Previously a single whisker sensor has been demonstrated mounted on a mobile robot for gathering information about the surface profile of objects close to the robot. This work has now been extended to an array of eight whiskers mounted on a robot that...

Mouse whiskers are somatotopically mapped in brainstem trigeminal nuclei as neuronal modules known as barrelettes. Whisker-related afferents form barrelettes in ventral principal sensory (vPrV) nucleus, whereas mandibular input targets dorsal PrV (dPrV). How barrelette neuron identity and circuitry is established is poorly understood. We found that ectopic Hoxa2 expression in dPrV neurons is su...

Visualization and tracking of the facial whiskers is required in an increasing number of rodent studies. Although many approaches have been employed, only high-speed videography has proven adequate for measuring whisker motion and deformation during interaction with an object. However, whisker visualization and tracking is challenging for multiple reasons, primary among them the low contrast of...

1. Single-unit responses to whisker deflections were studied in the rat somatosensory cortex (SI) under urethan anesthesia. 2. Experiments were concerned primarily with cortical layer V neurons, by selecting those units that 1) displayed initially positive biphasic spikes with an amplitude of at least 2 mV, 2) were located between 1,000 and 1,500 pm below the cortical surface of whisker C3 repr...