OBJECTIVE To investigate the impact of Withania somnifera roots on semen profile, oxidative biomarkers, and reproductive hormone levels of infertile men. DESIGN Prospective study. SETTING Departments of Biochemistry and Urology, Chhatrapati Shahuji Maharaj Medical University, Lucknow, India. PATIENT(S) Seventy-five normal healthy fertile men (control subjects) and 75 men undergoing infert...

an experiment was conducted to investigate the effects of fruit hydroalcoholic extract of withania coagulans (wc) and 1, 25-dihydroxycholecalciferol on bone mechanical and histological properties of male chickens. diets were arranged factorially (2×3×2) consisted of a positive control with adequate ca (10.4 g/kg diet) and nonphytate p (npp; 5 g/kg diet) exceed the requirements suggested in the ...

Medicinal plants are valuable and used for the synthesis of numerous drugs. Indigenous plants are traditionally used against various ailments. Present work is based on the research conducted on methanolic crude plant extracts of three medicinal plants of family solanaceae i.e. leaves of Datura inoxia Mill., Withania somnifera (L.) Dunal and Solanum surrattense were screened to investigate the b...

As a part of our research programme of investigating some medicinal plants cultivated in Beni-Suef Governorate (Egypt) as anticancer agents. Bioassay-guided fractionation study using brine shrimp lethality and Ehrlich Ascites carcinoma assays revealed that the PE extract (PE) of Withania somnifera (L.) Dunal leaves retained most cytotoxic activity among other extracts. The total phenolics, flav...

background and objective: temporal lobe epilepsy (tle) usually leads to memory deficit. in this study, we tried to assess the effect of withania somnifera extract on the impaired learning and memory in the intrahippocampal kainate model of tle in the rat. materials & methods: male rats (n=32) were divided into sham, extract+sham, kainite, and kainite+extract. for induction of epilepsy, uni...

Parkinson's disease remains as one of the most common debilitating neurodegenerative disorders. With the hopes of finding agents that can cure or reduce the pace of progression of the disease, we studied two traditional medicinal plants: Centella asiatica and Withania somnifera that have been explored in some recent studies. In agreement with the previous work on ethanol extracts of these two p...

The present study on effect of imidacloprid induced oxidative stress and its amelioration was carried out at definite time periods in different groups for 90 days on 48 layer birds of above 2 months age that were divided into six groups consisting of 8 in each. The birds were divided into group 1 was control, group 2 was treated with imidacloprid @ 200 ppm in feed, group 3 was treated with vita...

The immunosuppressive properties of an aqueous suspension of Withania somnifera (WS) root powder were investigated in a pristine induced female Balb/c model of a systemic lupus erythematosus (SLE) like disease. The course of disease is initiated by peritoneal inflammation caused by pristane which results in development of SLE like symptoms, i.e. autoantibody production, proteinuria, and nephrit...

Fifty 1-2-month-old Guinea pigs were divided into 5 equal groups, 10 each. Control (Gp1) did receive neither viable bacteria nor treatment. Each animal from the other groups (Gp2-5) was challenged with (1-2 × 10(8)) viable E. coli in 200  μ L normal saline (0.9%) through IP route. GP2 infected group was treated with 200  μ L saline IP and kept as positive control group. Gp3-4 are infected and t...