نتایج جستجو برای: wnt2 protein
تعداد نتایج: 1234770 فیلتر نتایج به سال:
RATIONALE Replication deficient adenoviruses (Ad) vectors are common tools in gene therapy. Since Ad vectors are known to activate innate and adaptive immunity, we investigated whether intratracheal administration of Ad vectors alone is sufficient to induce lung injury and pulmonary fibrosis. METHODS We instilled Ad viruses ranging from 107 to 1.625×109 ifu/mouse as well as the same volume of...
Adult stem cells continuously undergo self-renewal and generate differentiated cells. In the Drosophila ovary, two separate niches control germ line stem cell (GSC) self-renewal and differentiation processes. Compared to the self-renewing niche, relatively little is known about the maintenance and function of the differentiation niche. In this study, we show that the cellular redox state regula...
We introduce the notion of N-topo nilpotent fuzzy set in a fuzzy neighborhood ring and develop some fundamental results. Here we show that a fuzzy neighborhood ring is locally inversely bounded if and only if for all 0 < α < 1, the α-level topological rings are locally inversely bounded. This leads us to prove a characterization theorem which says that if a fuzzy neighborhood ring on a division...
We report an age-dependent increase in nonimmunohematopoietic cells (CD45neg) in regenerating muscle characterized by high stem-cell antigen (Sca-1) expression. In aged regenerating muscle, only 14% of these CD45negSca-1pos cells express MyoD, whereas 82% of CD45negSca-1(pos) cells are MyoDpos in young adult muscle. In vitro, CD45negMyoDnegSca-1pos cells overexpress fibrosis-promoting genes, po...
UNLABELLED Liver sinusoidal endothelium (LSEC) is a prime example of organ-specific microvascular differentiation and functions. Disease-associated capillarization of LSEC in vivo and dedifferentiation of LSEC in vitro indicate the importance of the hepatic microenvironment. To identify the LSEC-specific molecular differentiation program in the rat we used a two-sided gene expression profiling ...
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