We explore the estimation of uncertainty in evolutionary parameters using a recently devised approach for resampling entire additive genetic variance-covariance matrices (G). Large-sample theory shows that maximum-likelihood estimates (including restricted maximum likelihood, REML) asymptotically have a multivariate normal distribution, with covariance matrix derived from the inverse of the inf...

An automated PLS engine, WB-PLS, was applied to 1632 QSAR series with at least 25 compounds per series extracted from WOMBAT (WOrld of Molecular BioAcTivity). WB-PLS extracts a single Y variable per series, as well as pre-computed X variables from a table. The table contained 2D descriptors, the drug-like MDL 320 keys as implemented in the Mesa A&C Fingerprint module, and in-house generated top...

The main objective of the present study was to estimate genetic and phenotypic trends for body weight traits in Guilan province sheep. Traits included were birth weight (BW, n=14,549), 3-month weight (3MW, n=13,109) and 6-month weight (6MW, n=10,141). Data and pedigree information used in this study were collected during 1994 to 2011 by the Agricultural Organization of Guilan province in Iran. ...

Abstract Embryonic development in mammals is strictly controlled. Yet, anomalies regularly occur within certain species. The pig one of few species where variation vertebra numbers frequently occurs. Domesticated lines typically have a greater number thoracic and/or lumbar than the vertebrae most mammals. Number functional teats also variable swine and deviation from bilateral symmetry common. ...

the objective of this study was to estimate genetic parameters coupled with genetic and phonotypic trends for age at first calving (afc), open days(od) and milk yield(my) of first lactation in iranian holstein cows. records of reproduction and production for genetic evaluation from 1984 to 2005 for afc, od and my were 71736, 20126 and 20126, respectively. single and two-variable animal models w...

in this research genetic and phenotypic parameters were estimated using linear and threshold models, for reproductive traits, data from 6 large industrial dairy herd of east azerbaijan province collected by agriculture jihad organization during 10 years (2001-2010). best linear unbiased predictions of traits breeding values were estimated using restricted maximum likelihood method by wombat sof...

the data of this study were collected by indigenous chicken breeding centers in the west azerbaijan for 11 generations. the (co) variance components, heritability's, correlations between traits and breeding values were estimated by multi-trait animal model using wombat software. the genetic trends of traits over 11 generations of selection, using average function of breeding values per gen...