an admirably clear description of the skin lesions in Xanthoma Diabeticorum, that it still remains unsurpassed. In describing the skin lesion of their diabetic patient, the authors wrote: ' An eruption somewhat suddenly appeared on the arms, at first apparently of a lichenous character. In the course of 10 days, it had extended over the arms, legs and trunk, both anteriorly and posteriorly, and...

An Ix-year-old Caucasian boy was seen at the Indiana University Medical Center, Department of Ophthalmology, because of a yellow limbal lesion of the left eye which had been first noted 2 years previously, and which had been progressively enlarging. The family history was not contributory. The child was premature, but developed normally with no history of significant systemic or ocular disease....

Xanthomatous skin lesions and arthritis in children are not a common association. We present the case of a 3 year old girl who presented with xanthomatous lesions in the periungual region of both hands, around the nares and on her forehead, associated with significant arthritis that was clinically compatible with multicentric reticulohistiocytosis. However, pathology of the xanthomatous lesions...

Cystoscopy is most common diagnostic investigation. The examination technique and the findings, both normal and pathological, were well described described a hundred years ago. With technological advances, there has been over-emphasis on imaging modalities for diagnostic purposes. A basic maneuver of examining the ureteral orifices is sometimes rushed through when in fact careful examination ca...