Four Chinese patients with xeroderma pigmentosum (XP), who had different degrees of skin symptoms, were tested for their genetic complementation groups. Skin fibroblasts obtained from the patients were used for complementation analysis done by a cell-fusion technique. Three of the patients belonged to group C and one, who had the mildest cutaneous manifestations, to group E. This is the first r...

This paper is a partial summary of the survey paper [1]. In particular, we are interested in telling the following story: given a lattice polytope, P , one would like to find an efficient way of counting the lattice points contained in P . One of the nicest ways to accomplish this is to use algebraic geometry in a clever and beautiful way. Namely, from P one can construct a toric variety, XP , ...

The Sonic hedgehog (SHH) pathway is implicated in the etiology of the most common human cancer in Caucasians, the basal cell carcinoma (BCC). Mutations in the receptor of SHH, the patched gene, have been characterized in sporadic BCCs as well as those from patients with the rare genetic syndromes nevoid BCC and xeroderma pigmentosum (XP). To elucidate the role of UV in the deregulation of the S...

Most standard software development methodologies are often not applied to software projects in many developing countries of the world. The approach generally practice is close to what eXtreme Programming (XP) is likely promoting, just keep coding and testing as the requirement evolves. XP is an agile software process development methodology that has inherent capability for improving efficiency ...

—Agile is one of the terms with which software professionals are quite familiar. Agile models promote fast development to develop high quality software. XP process model is one of the most widely used and most documented agile models. XP model is meant for small-scale projects. Since XP model is a good model, therefore there is need of its extension for the development of medium and large-scale...

XPD functions in transcription, DNA repair and in cell cycle control. Mutations in human XPD (also known as ERCC2) mainly cause three clinical phenotypes: xeroderma pigmentosum (XP), Cockayne syndrome (XP/CS) and trichothiodystrophy (TTD), and only XP patients have a high predisposition to developing cancer. Hence, we developed a fly model to obtain novel insights into the defects caused by ind...

Extreme Programming (XP) is inherently collaborative, which makes it amenable to Computer Supported Cooperative Work (CSCW) support. The collaboration enabling tools and techniques used in XP, such as whiteboards, index cards and co-location, are adequate for their immediate purposes. However, they do not allow sufficient information to survive beyond the end of projects. Long term consequences...

Analysis of transcription-coupled repair (TCR) of oxidative lesions here reveals strand-specific removal of 8-oxo-guanine (8-oxoG) and thymine glycol both in normal human cells and xeroderma pigmentosum (XP) cells defective in nucleotide excision repair. In contrast, Cockayne syndrome (CS) cells including CS-B, XP-B/CS, XP-D/CS, and XP-G/CS not only lack TCR but cannot remove 8-oxoG in a transc...

Extreme Programming (XP) is a light-weight software engineering methodology conceived by KENT BECK with a strong focus on business value. Design by Contract is a software design technique defined by BERTRAND MEYER that stresses stability and maintainability of large systems. The two are regarded as incompatible by many of their respective followers. In this paper, the authors describe why contr...

Introduction For p, a countable similarity type, let Xp be the space of structures of similarity type p whose universe is ω (see [13], Section 3). For any element & of Xp, let \d/\ be the set of all elements of Xp which are isomorphic to CO. Scott [10] showed that \β/\ is a Borel subset of Xp. In fact, he showed that for any such (2/ there is a sentence θ of Lωχω such that \C0\ is exactly the s...