BACKGROUND A standard treatment for unresectable advanced-stage intrahepatic cholangiocarcinoma (IHCC) has not yet been established. Although neoadjuvant concurrent chemoradiotherapy (CCRT) and liver transplantation are associated with long-term survival in select patients, the outcomes of CCRT for advanced-stage unresectable IHCC remain unclear. The aim of our study was to evaluate the outcome...

The Extreme Programming development Methodology (XP) seems appropriate for some teams or projects. Anecdotal stories from developers who have tried XP are often favorable. However, there is little empirical evidence to support or refute claims regarding XP. The Extreme Programming Evaluation Framework (XPEF) provides a benchmark measurement framework for researchers and practitioners to assess ...

Abstract. Aksomaitis and Burauskaite-Harju [Information Technology and Control, 38, 2009, 301-302] studied the distribution of max(X1, X2,..., Xp) when (X1, X2,..., Xp) follows the multivariate normal distribution. Here, we study the moments of min(X1, X2,..., Xp) and max(X1, X2,..., Xp) when (X1, X2,..., Xp) follows the most commonly known multivariate Pareto distribution. Multivariate Pareto ...

Forty-eight barrows and forty-eight gilts (PIC 337 sires x PIC C22 dams) were evaluated to determine the effects of feeding ractopamine hydrochloride (RAC) and different cereal grains on the carcass and fat quality in late finishing pigs. The study was carried out using four replicates with 24 animals in each replicate (four pigs per pen, six pens per replicate, two replicates per slaughter dat...

A transgenic line of Yorkshire (YK) pigs named the Cassie (CA) line was produced with a low copy number phytase transgene inserted in the genome. The transgenic line efficiently digests P, Ca, and other major minerals of plant dietary origin. The objectives of this study were to 1) compare carcass and tissue nutrient composition and meat quality traits for third generation hemizygous CA line ma...

moderate to excellent entantio- and stereoselectivities (ee’s 54-100%) were observed in ple catalyzed hydrolysis of (±)-ethyl 5-oxo-endo-tricyclo[5.2.1.02,6] deca-8-ene-2-carboxylate 5 and the structurally related open chain bicyclic structures (±)-ethyl 3-acetylbicyclo[2.2.1]hept-5-ene-2-carboxylates 7, 9 and (±)-ethyl 3-propanoylbicyclo[2.2.1]hept-5-ene-2-carboxylates 8, 10. a pronounced pref...

Escrow.com began implementation of XP as its development process in December 2000, in parallel with other significant organizational changes. This document describes the philosophical, logistical, physical and organizational changes that occurred both to enable XP implementation, and as a result of XP implementation. Implementation challenges as well as ongoing benefits of the XP process are di...

Xeroderma pigmentosum variant (XP-V) is a subtype of xeroderma pigmentosum (XP) disease with typical pigmentation and types of cancer in the oral maxillofacial and other sun-exposed regions. Few factors of tumor proneness in XP-V have been completely elucidated with the exception of the POLH [which encodes DNA polymerase η (pol η)] mutation. The aim of the present study was to identify the POLH...

Xeroderma pigmentosum (XP) is one of a number of autosomal recessive syndromes in humans characterized by a marked predisposition to cancer. Fibroblasts from these patients show a defect in DNA repair. The XP heterozygotes also show elevated skin cancer incidence, but reports concerning their DNA repair capacity are conflicting. In this study, the DNA repair capacity of four XP heterozygotes wa...