Array-based comparative genomic hybridization (CGH) measures copy-number variations at multiple loci simultaneously, providing an important tool for studying cancer and developmental disorders and for developing diagnostic and therapeutic targets. Arrays for CGH based on PCR products representing assemblies of BAC or cDNA clones typically require maintenance, propagation, replication, and verif...

       Heat stroke is the most complicated and dangerous amongst heat injuries that can lead to irreversible injury and even death with itself or with creating predisposibility to different diseases. The following case report depicts a patient who presented primarily with impairment of consciousness after walking 45 km in the summer heat to cross the Syria-Turkey border and la...

XX male is a kind of sexual differentiation disorder that affects one out of every 20,000 to 25,000 male births. The patients have male phenotypes with female chromosomes, the karyotype 46XX. More than 150 XX males have been reported in the medical literature since Albert de la Chapelle first reported a male human with a pure XX sex chromosome constitution in 1964.1,2 Most patients with this co...

We tested the role of sex chromosome complement and gonadal hormones in sex differences in several different paradigms measuring nociception and opioid analgesia using "four core genotypes" C57BL/6J mice. The genotypes include XX and XY gonadal males, and XX and XY gonadal females. Adult mice were gonadectomized and tested 3-4 weeks later, so that differences between sexes (mice with testes vs....

Dystonia associated with chromosomal abnormalities is typically attributed to chromosomal deletions. We describe a patient with ring chromosome 21, with karyotype 46XX,r(21)(p11.2q22.3); 46,XX,dic r(21)(p11.2q22.3); 45, XX, -21, who developed childhood onset cervical dystonia.

background and objective: pregnancy termination and recurrent abortion are one of the common complications during pregnancy and in patients with a bad obstetric history. materials and methods: in this study, a total of 154 individuals including 75 couples four single women from different communities and with various incomes were investigated chromosomal abnormalities using blood culture and chr...

In Drosophila, the sex of XX germ cells is determined by somatic signals. Whether sex-specific genes, however, are activated or repressed by somatic signals is not known. We have used mgm1, a germline-marker which is specifically expressed in male germ cells to analyze sex-specific gene expression of embryonic germ cells. We found that XX and XY germ cells that do not contact gonadal tissue can...

Accepted xx-xx-xxxx; Received xx-xx-xxxx ABSTRACT The proximity eeect of metal line absorption systems in spectra of high redshift quasars and quasar pairs is investigated through the distribution of Ly forests. No strong proximity eeect is found down to 500 km/sec away from a metal line absorption system for lyman clouds with 13:3 log N HI < 13:8 at a redshift of 3. Its implication on properti...

This paper addresses the problem of generating strong convex relaxations of Mixed Integer Quadratically Constrained Programming (MIQCP) problems. MIQCP problems are very difficult because they combine two kinds of non-convexities: integer variables and nonconvex quadratic constraints. To produce strong relaxations of MIQCP problems, we use techniques from disjunctive programming and the liftand...

In this paper we studied the thermal negativity in a two-qubit XX spin ½ chain model and XXX spin1/2 chain model(isotropic Heisenberg model)spin-1/2 chain subjected to an external magnetic field inz direction. We calculate analytical relation for the thermal negativity for two qubit XX and XXX spinchain models in the external magnetic field. Effects of the magnetic field and temperature on then...