Numerous factors can affect skeletal regeneration, including the extent of bone injury, mechanical loading, inflammation and exogenous molecules. Bisphosphonates are anticatabolic agents that have been widely used to treat a variety of metabolic bone diseases. Zoledronate (ZA), a nitrogen-containing bisphosphonate (N-BP), is the most potent bisphosphonate among the clinically approved bisphosph...

Adresa za dopisivanje Ivan Galić Dom zdravlja Splitsko-dalmatinske županije Stomatološka ordinacija – Kamenmost Kamenmost bb, 21262 Kamenmost Tel: +385 21 848 052 Fax: +385 21 848 052 [email protected] Sažetak Određivanje dentalne dobi kod djece u razvoju važno je u pedodonciji, ortodonciji i forenzičnoj znanosti. Najčešće se primjenjuje postupak prema Demirjianu nastao na francusko-kanadskom uzo...

The epithelial Zonula adherens (ZA) is a main adhesion compartment that enables organogenesis by allowing epithelial cells to assemble into sheets. How ZA assembly is regulated during epithelial cell morphogenesis is not fully understood. We show that during ZA morphogenesis, the function of the small GTPase Rap1 and the F-actin binding protein AF6/Cno are both linked to that of the P21-activat...

Adresa za dopisivanje Dr. Seema R. Hallikerimath MDS Professor and Head KLE VK Institute of Dental College Nehru nagar Belgaum-590010, Karnataka, Indija Faks. (0831) 2470640 Tel: +919448110562 [email protected] Sažetak Juvenilna hijalina fibomatoza iznimno je rijedak poremećaj kod dojenčadi i djece, a javlja se prema zakonima autosomno recesivnog nasljeđivanja. Izgleda poput multiple kož...

BACKGROUND To study the effects of zoledronic acid (ZA) on the vasculogenic mimicry of osteosarcoma cells in vitro. METHODS A Three-dimensional culture of LM8 osteosarcoma cells on a type I collagen matrix was used to investigate whether osteosarcoma cells can develop vasculogenic mimicry, and to determine the effects of ZA on this process. In addition, the cellular ultrastructural changes we...

The aim of this study was to evaluate the effect of zoledronic acid (ZA) on bone mineral density (BMD) in patients with prostate cancer receiving combined androgen blockade (CAB) as a first-line androgen deprivation therapy. Patients receiving CAB for prostate cancer without bone metastasis were candidates for this study. Forty-two patients were randomly assigned to receive either ZA or no trea...

The zonula adherens (ZA), a type of adherens junction (AJ), plays a major role in epithelial cell-cell adhesions. It remains unknown how the ZA is remodeled during epithelial reorganization. Here we found that the ZA was converted to another type of AJ with punctate morphology (pAJ) at the margins of epithelial colonies. The F-actin-stabilizing protein EPLIN (epithelial protein lost in neoplasm...

A strain of Tick-borne encephalitis virus designated Zausaev (Za) was isolated in Siberia from a patient who died of a progressive (2-year) form of tick-borne encephalitis 10 years after being bitten by a tick. The complete genomic sequence of this virus was determined, and an attempt was made to correlate the sequence with the biological characteristics of the virus. Phylogenetic analysis demo...

For the zonula adherens (ZA) to be established by linear-arrangement of adherens junctions (AJs) in epithelial sheet cells, critical for the epithelial cell sheet formation and intercellular barrier function, myosin-2 is supposedly integrated into the ZA with the result of overlapping localization of E-cadherin/actin/myosin-2. Here we immunofluorescently showed that myosin-2 failed to be integr...

In Chinese, anaphors are frequently omitted, termed zero anaphor (ZA), from text due to their prominence. Thus the information carried by ZAs in text can not be used to contribute the calculation of text categorization. In this paper, we employ a ZA resolution method to recover the omissions of anaphors in text. Then the resulting text is used as the input of a text categorization system. The e...