Alzheimer's disease (AD) and diabetes mellitus (DM) are related to abnormal changes in enzyme activity. While acetylcholinesterase (AChE) butyrylcholinesterase (BChE) the primary targets treatment of (AD), α-glucosidase (α-Gly) α-amylase (α-Amy) enzymes known for (DM). Here, benzenesulfonamide-based thiourea thiazolidinone derivatives such as AChE, BChE, α-Gly, α-Amy inhibitors were reported. T...

Hybrid manufacturing (HM) Ti-6Al-4V components combining the advantages of forging and additive were achieved. The bonding zone HMed component joins substrate manufactured its α′-α/α′/αm-α/β heterogeneous microstructure was attributed to distinguishing cooling rate pseudo-isothermal annealing temperature. phase transformation mechanisms clarified with a numerical simulation model for thermal an...