In our research, new bis-α, β-unsaturated carbonyl compounds (Z2-Z4) were prepared via Claisen- Schmidt reaction, by the condensation of 2,6-dimethyl-3,5-diacetyl-1,4-dihydropyridine (Z1) with different appropriate benzaldehyde, like (benzaldehyde, m-nitro benzaldehyde and o-chloro benzaldehyde) using 10% aqueous sodium hydroxide as a base. A simple efficient method has been applied for synthes...

In humans, 5alpha-reductase is involved in the development of benign prostatic hyperplasia. Triterpenoids isolated from ethanol extracts of Ganoderma lucidum (Fr.) Krast (Ganodermataceae) inhibited 5alpha-reductase activity. The presence of the C-3 carbonyl group and of the C-26-alpha,beta-unsaturated carbonyl group was characteristic of almost all inhibitors isolated from G. lucidum.

The first iridium-catalyzed enantioselective allylic alkylation of an olefinic C(sp2)–H bond – that ?,?-unsaturated carbonyl compound, is developed in cooperation with Lewis base catalysis.

A study of the relative effectiveness of some eighteen natural and synthetically modified cytochalasins on the uptake of glucose by the Gram-positive bacterium Arthrobacter sialophilus showed that cytochalasins B, C or D and aspochalasins A, C or D were inactive natural congeners. The presence of an alpha,beta-unsaturated carbonyl group in the macrolide moiety of these compounds with appropriat...

In this review, we summarize research efforts to realize Na-based organic materials for novel battery chemistries. Na is a more abundant element than Li, thereby contributing to less costly materials with limited to no geopolitical constraints while organic electrode materials harvested from biomass resources provide the possibility of achieving renewable battery components with low environment...

The 1,4-conjugate addition of nucleophiles to α,β-unsaturated carbonyl compounds represents one fundamental bond-forming reaction in organic synthesis. The development of effective organocatalysts for the enantioselective conjugate addition of malonate, nitroalkane and other carbon and heteroatom nucleophiles to cycloenones constitutes an important research field and has been explored in recent...