Background Lysosomal storage disease (LSD) is a rare inherited disease group. Consecutively there are few data on cardiac changes in mucopolysaccharidosis (MPS), Anderson Fabry disease (AFD), and other LSD (oLSD) including Pompe disease (PD) and Danon disease (DD), I-cell disease ICD and mucolipidosis III (ML III). Methods Between 1994 and 2011, we identified 39 patients with LSD: 25 with MPS...

Potent serotonin (5-HT) reuptake inhibitors are the only drugs that consistently exert a therapeutic action in obsessive-compulsive disorder (OCD). Given that some hallucinogens were reported to exert an anti-OCD effect outlasting their psychotomimetic action, possible modifications of neuronal responsiveness to 5-HT by LSD were examined in two rat brain structures: one associated with OCD, the...

Slices of rat hypothalamus prelabeled with [3H]-5-hydroxytryptamine ([3H]-5-HT) were superfused and the release of the labeled transmitter was elicited either by electrical stimulation or by fenfluramine. Whereas the electrically stimulated release of [3H]-5-HT was completely abolished by removing calcium from the superfusion medium, the fenfluramine-induced release of [3H]-5-HT was calcium-ind...

LSD is a linear-time Line Segment Detector giving subpixel accurate results. It is designed to work on any digital image without parameter tuning. It controls its own number of false detections: on average, one false alarm is allowed per image [1]. The method is based on Burns, Hanson, and Riseman’s method [2], and uses an a contrario validation approach according to Desolneux, Moisan, and More...

Broadcast Encryption schemes enable a center to broadcast encrypted programs so that only designated subsets of users can decrypt each program. The stateless variant of this problem provides each user with a fixed set of keys which is never updated. The best scheme published so far for this problem is the “subset difference” (SD) technique of Naor Naor and Lotspiech, in which each one of the n ...