N ear-infrared (NIR) optical tomography is a non-invasive diagnostic imaging technique that has the potential of acquiring unique tissue-specific contrast. The high contrast of NIR optical tomography originates from the stronger light attenuation by hemoglobin relative to water in parenchymal tissue, as well as the distinct spectral differences of hemoglobin between the oxygenated and deoxygena...

Lestander, T. A. 2003. Multivariate NIR studies of seed-water interaction in Scots pine seeds (Pinus sylvestris L.). Doctoral dissertation. This thesis describes seed-water interaction using near infrared (NIR) spectroscopy, multivariate regression models and Scots pine seeds. The presented research covers classification of seed viability, prediction of seed moisture content, selection of NIR w...

Fluorescence lifetime (FLT) properties of organic molecules provide a new reporting strategy for molecular imaging in the near infrared (NIR) spectral region. Unfortunately, most of the NIR fluorescent dyes have short FLT typically clustered below 1.5 ns. In this study, we demonstrate that a new class of NIR fluorescent dyes, pyrrolopyrrole cyanine dyes, have exceptionally long FLTs ranging fro...

Near Infrared (NIR) spectroscopy has been used for timber, pulp and paper applications for over 20 years. Despite a lot of R&D work on solid wood applications for both field and in-process use, the industry has not adopted NIR as a routine technique. Solid wood has proven to be a challenging sample type to analyse in real time by NIR as the modern timber mill processes logs at a very fast rate....

Near-infrared (NIR) light-responsive liposomes are attractive carriers for targeted and controlled drug delivery to the superficial organ or tissue (e.g., skin). This work describes the development of NIR-responsive liposomes by incorporating gold nanostars within liposomes composed of Phospholipon 90 g and cholesterol. Following cellular delivery, photothermal effect around the gold nanostar u...

Several advantages of the near-infrared (NIR) technique in the characterization of the secondary structure of regenerated Bombyx mori silk fibroin are demonstrated. Silk fibroin films with thicknesses ranging from 50 to 300 microm are suitable for the NIR measurement. The bands due to hydrogen-bonded water are independent in the NIR spectra and facilitate our investigation of the amide region. ...

With the emerging interest in optical in vivo imaging, there is an increasing demand of photostable near-infrared (NIR) dyes. Herein we report the rational design of an amine tricarbocyanine structure with improved photostability (CyNA) and its combinatorial derivatization to render CyNA-414 as a NIR-fluorescent dye with stronger emission intensity and higher photostability than the NIR standar...

A novel sandwich nanomedicine (GO-BNN6) for near-infrared (NIR) light responsive release of nitric oxide (NO) has been constructed by self-assembly of graphene oxide (GO) nanosheets and a NO donor BNN6 through the π-π stacking interaction. The GO-BNN6 nanomedicine has an extraordinarily high drug loading capacity (1.2 mg BNN6 per mg GO), good thermal stability, and high NIR responsiveness. The ...

In vivo trans-rectal near-infrared (NIR) optical tomography was performed concurrently with, albeit reconstructed without spatial a prior of, trans-rectal ultrasound (US) on transmissible venereal tumor (TVT) developed as a model in the canine pelvic canal. Studies were taken longitudinally at prior to, 14 days after, and 35 days after the TVT injection. As the tumor grew, the nodules became in...

We present the results of X-ray and near-infrared (NIR) observations of L1448, a star-forming region in the Perseus cloud complex using the Chandra X-ray Observatory and the 4 m telescope at the Kitt Peak National Observatory. We detect 72 X-ray sources in a ∼17 ′ ×17 ′ region with a ∼68 ks ACIS exposure, for which we conduct follow-up NIR imaging observations in a concentric ∼11 ′ ×11 ′ region...