Streptococcus pyogenes is an important human pathogen and surface structures allow it to adhere to, colonize and invade the human host. Proteins containing leucine rich repeats (LRR) have been indentified in mammals, viruses, archaea and several bacterial species. The LRRs are often involved in protein-protein interaction, are typically 20–30 amino acids long and the defining feature of the LRR...

• Set out more clearly the underlying philosophy of cost analysis and management in official DH documents. • Develop training for NHS staff in the roles and potentials of appropriately constructed cost information. • Develop the evidence base on the potential and effectiveness of SLR and PLICS. Executive summary The NHS faces major cost reductions in the coming years. Two new costing tools are ...

Background: Our research group is developing and documenting procedures for undertaking systematic literature reviews (SLRs) within the software engineering domain. A question that has arisen is whether the procedures are suitable for use by students over a relatively short period of time. A further question is related to the effectiveness of pair programming for undergraduate students. Aims: T...

CONTXEXT:-Software outsourcing partnership (SOP) is a relationship between client and vendor organizations for shared goals. A SOP is different than ordinary outsourcing contractual relationship. Usually a successful outsourcing relationship may lead to outsourcing partnership. OBJECTIVE:-The objective of this research is to identify factors via systematic literature review (SLR), that are sign...

[Purpose] The purpose of this study was to identify how spinal decompression therapy and general traction therapy influence the pain, disability, and straight leg raise (SLR) ability of patients with intervertebral disc herniation. [Subjects] The subjects were 30 patients with chronic lumbar pain who were divided into a spinal decompression therapy group (SDTG, n=15), and a general traction the...

LIN-35 is the sole C. elegans representative of the pocket protein family, which includes the mammalian Retinoblastoma protein pRb and its paralogs p107 and p130. In addition to having a well-established and central role in cell cycle regulation, pocket proteins have been increasingly implicated in the control of critical and diverse developmental and cellular processes. To gain a greater under...

Mean sea level has risen tenfold in recent decades compared to the most recent millennia, posing a serious threat for population and assets in flood-prone coastal zones over the next century. An increase in the frequency of nuisance (minor) flooding has also been reported due to the reduced gap between high tidal datums and flood stage, and the rate of sea level rise (SLR) is expected to increa...

The impacts of sea-level rise (SLR) on coastal ecosystems have attracted worldwide attention in relation to global change. In this study, the salt marsh model for the Yangtze Estuary (SMM-YE, developed in China) and the Sea Level Affecting Marshes Model (SLAMM, developed in the U.S.) were used to simulate the effects of SLR on the coastal salt marshes in eastern China. The changes in the domina...

Systematic Literature Review (SLR) is a rigorous methodology applied for Evidence-Based Software Engineering (EBSE) that identify, assess and synthesize the relevant evidence for answering specific research questions. Benefiting from the booming online materials in the era of Web 2.0, the technical Web content starts acting as alternative sources for EBSE. Web knowledge has been investigated an...